Results 141 to 150 of about 1,197,836 (289)
Molecular Oncology, EarlyView.Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi +12 more
wiley +1 more source
Study the Readiness of State hospitals in Ilam Province in the Face of Natural Disasters
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2018 Introduction: Crises are usually unexpectedly appearing, resulting in hidden and obvious consequences, so managers must always be prepared to deal with them in the right way.
Esfandyar Mohammadi
doaj
Questionable care: avoiding ineffective treatment [PDF]
Overview In some hospitals, far too many people get a treatment they should not get, even when the evidence is clear that it is unnecessary or doesn’t work. Australia urgently needs a system to identify these outlier hospitals and make sure they are not
Peter Breadon, Stephen Duckett
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Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
How Does Payer Mix and Technical Inefficiency Affect Hospital Net Revenue? [PDF]
As changes in the US health care system continue to evolve and change, maintaining the financial viability of hospitals is crucial to the system’s operation. Two lines of inquiry have been pursued in describing factors affecting financial viability.
Hervé Leleu +2 more
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Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Molecular Oncology, EarlyView.Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza +5 more
wiley +1 more source
Public problems: private solutions? Short-term contracting of inpatient hospital care [PDF]
Executive summary Public patients are routinely being treated in Australian private hospitals. Some jurisdictions have large-scale, planned programs where private or not-for-profit hospitals are contracted by the public sector to treat public inpatients
Anne-Marie Boxall +2 more
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Molecular Oncology, EarlyView.RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
State HAI progress : acute care hospitals [PDF]
2016 HAI progress report, acute care hospitals, CLABSI, SSI, CAUTI, MRSA, C.difficile, national HAI progress report, state HAI progress report, NHSN data, LTACH, LTC, SIRTHIS REPORT IS BASED ON 2014 DATA, PUBLISHED IN 2016Publication date from document ...
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