Results 141 to 150 of about 13,356,795 (360)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Estimating Variability in Hospital Charges: The Case of Cesarean Section [PDF]

arXiv
This study sought to better understand the causes of price disparity in cesarean sections, using newly released hospital data. Beginning January 1, 2021, Centers for Medicare and Medicaid Services (CMS) requires hospitals functioning in the United States to publish online pricing information for items and services these hospitals provide in a machine ...
arxiv  

Ownership and Financial Performance in the German Hospital Sector [PDF]

This paper considers the role of ownership form for the financial performance of German acute care hospitals and its development over time.We measure financial performance by a hospital-specific yearly probability of default (PD).
Boris Augurzky, Christoph M. Schmidt, Christoph Schwierz, Dirk Engel   +3 more
core  

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Atherogenic Index of Plasma and its Relationship with Cardiovascular Risk Factors Among Adult Patients Attending a Primary Care Clinic in South West Nigeria

Nigerian Frontline Medicine Journal
Background: Cardiovascular diseases have remained major causes of death globally. Early identification of individuals at risk of cardiovascular disease and appropriate intervention is needed in order to reduce the disease burden. The Atherogenic index of
Adeyinka O. Ilesanmi, Ibrahim S. Bello, Akinjide O. Ogundokun, Oluwafemi T. Ile, Azeez O. Ibrahim, Samuel A. Olowookere   +5 more
doaj  

Promoting childbirth companions in South Africa: a randomised pilot study

BMC Medicine, 2007
Background Most women delivering in South African State Maternity Hospitals do not have a childbirth companion; in addition, the quality of care could be better, and at times women are treated inhumanely.
Smith Helen, Nikodem V Cheryl, Hofmeyr G Justus, Brown Heather, Garner Paul   +4 more
doaj   +1 more source

The Tax Benefits of Not-for-Profit Hospitals [PDF]

This paper investigates three special tax provisions for not-for-profit (NFP) hospitals. First taxes -- both income and property taxes. Second, they issue tax-exempt bonds so lenders do not pay income taxes on interest received.
John R. Penrod, William N. Gentry
core  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Wilm’s tumor presenting with scrotal varicocele in an 11-month-old boy

Indian Journal of Radiology and Imaging, 2018
This is a case report of Wilms’ tumor which presented with varicocele in an 11-month old infant. The age of the patient and the uncommon mode of presentation are the unique features of this case.
Bukunmi M Idowu, Adebayo G Tanimola
doaj   +1 more source

Forecasting Influenza Hospitalizations Using a Bayesian Hierarchical Nonlinear Model with Discrepancy [PDF]

arXiv
The annual influenza outbreak leads to significant public health and economic burdens making it desirable to have prompt and accurate probabilistic forecasts of the disease spread. The United States Centers for Disease Control and Prevention (CDC) hosts annually a national flu forecasting competition which has led to the development of a variety of flu
arxiv