Results 141 to 150 of about 13,331,196 (287)

Correlation between shift work and psychological problems among hospitals personnel of Ardabil University of Medical science [PDF]

open access: yes
Background Shift work can be propounded as a risk factor of psychological problems creation. This study has been executed to determine relation between shift work and psychological problems among hospital’s personnel of Ardabil University of Medical ...
درخشانی, فاطمه   +5 more
core  

International Profiles of Health Care Systems [PDF]

open access: yes, 2010
Compares the healthcare systems of Australia, Canada, Denmark, England, France, Germany, Italy, the Netherlands, New Zealand, Norway, Sweden, Switzerland, and the United States, including spending, use of health information technology, and ...

core  

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Money, Politics, and Impartial Justice [PDF]

open access: yes, 2009
A centuries-old controversy asks whether judicial elections are inconsistent with impartial justice. The debate is especially important because more than 90 percent of the United States\u27 judicial business is handled by state courts, and approximately ...
Shepherd, Joanna M.
core   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Evaluation of ergonomics awareness and its lack of application on medical laboratory practitioners in tertiary hospitals in Jos, Plateau, Nigeria

open access: yesInternational Journal of Medicine and Health Development
Background: The study of how people interact with their work environment is known as ergonomics. Medical laboratory practitioners are exposed to work-related musculoskeletal disorders, resulting in a reduction in the quality of health care services ...
Bamidele O Olumide   +9 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Minnesota Hospitals’ Plans for Implementing Statewide Guidance on Allocation of Scarce Critical Care Resources During the COVID-19 Pandemic

open access: yesMayo Clinic Proceedings: Innovations, Quality & Outcomes
Objectives: To assess hospitals’ plans for implementing Minnesota’s statewide guidance for allocating scarce critical care resources during the COVID-19 pandemic.
Kirsten A. Riggan, MS, MA   +7 more
doaj   +1 more source

Home is Where the Hurt is: An Econometric Analysis of Injuries Caused By Spousal Assault [PDF]

open access: yes
Using data on injuries presenting at the emergency departments of participating hospitals in the Australian state of Queensland we examine the nature of injuries resulting from spousal assault and compare them to injuries from nonspousal assault and ...
Borooah, Vani, Mangan, John
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

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