Results 111 to 120 of about 3,338,966 (306)

Age‐Related Lamin B1 Deficiency Activates SLC7A11‐Dependent Disulfidptosis to Impair Osteogenesis via Intercepting Mitochondrial Fission

Advanced Science, EarlyView.
This study reveals that age‐related LMNB1 deficiency in mesenchymal stem cells epigenetically upregulates SLC7A11, triggering actin disulfidptosis and mitochondrial dysfunction. This cascade impairs bone formation in senile osteoporosis. Furthermore, researchers identified the FDA‐approved drug naldemedine as a targeted SLC7A11 inhibitor to reverse ...
Wenhui Yu, Qibo Li, Weihao Zhang, Guan Zheng, Junhua Chen, Yipeng Zeng, Zipeng Xiao, Zibin Chen, Ziqian Liu, Yangfeng Lin, Jiajie Lin, Zepeng Su, Zhongyu Xie   +12 more
wiley   +1 more source

American Women's Hospitals Service photographs: France, circa 1920, 1948

, 1918
The American Women's Hospitals (AWH) developed from the War Service Committee of the Medical Women's National Association (later, American Medical Women's Association (AMWA)) in 1917 to provide, register and finance American women physicians for war work;

core   +1 more source

Estimation of the Romanian hospitals efficiency in relation to hospital market competition [PDF]

The study examines a sample of 20 teaching and research Romanian hospitals, located in Bucharest, during the period 2001 – 2005, in terms of their efficiency and influence on their neighbouring health care units, expressed as an idiosyncratic form of ...
Mihaela Cornelia PREJMEREAN, Simona VASILACHE   +1 more
core  

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

AGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

Barbed Sutures Are Associated With a Lower Incidence of Incisional Hernia Compared With Continuous Non‐Barbed Monofilament Sutures After Minimally Invasive Gastroenterological Surgery

Annals of Gastroenterological Surgery, EarlyView.
Incisional hernia remains a common complication after minimally invasive gastroenterological surgery despite small extraction incisions. In this propensity score‐weighted analysis, barbed sutures significantly reduced the incidence of incisional hernia compared with conventional slowly absorbable monofilament sutures without increasing postoperative ...
Shusaku Honma, Takashi Takashima, Tatsuhi Ushikubo, Kana Ishikawa, Takashi Kumode, Takahisa Suzuki, Teppei Murakami, Shinichi Hosokawa, Sanae Nakajima   +8 more
wiley   +1 more source

American Women's Hospitals Service photographs: Yugoslavia - Serbia, circa 1920

, 1919
The American Women's Hospitals (AWH) developed from the War Service Committee of the Medical Women's National Association (later, American Medical Women's Association (AMWA)) in 1917 to provide, register and finance American women physicians for war work;

core   +2 more sources

American Women's Hospitals Service photographs: Albania, 1919, undated

, 1919
The American Women's Hospitals (AWH) developed from the War Service Committee of the Medical Women's National Association (later, American Medical Women's Association (AMWA)) in 1917 to provide, register and finance American women physicians for war work;

core  

A Multistrategy AI‐Assisted Consensus Screening Pipeline for Discovery of Candidate p53 Monomer Binders

Advanced Intelligent Discovery, EarlyView.
An ultra‐fast small‐sample AI consensus pipeline combines co‐folding and docking to target structure‐lacking p53 monomers. Its optimal mini‐protein binder shows robust interfacial affinity and promising druggability, supplying unprecedented antitumor p53 templates.
Ningyao Li, Xueyi Liu, Qiuyue Li, Chengfeng Yue, Xin Li, Yugang Huang, Xin Deng, Junfei Zhang, Xue Liang, Guodong Ye   +9 more
wiley   +1 more source

Dr. Gray and Mrs. Cruikshank, of the American Women's Hospitals, at Veles, Serbia

, 1920
Dr. Gray, director of American Women's Hospitals, and Mrs.

core  

U‐Net‐Based Prediction of Concealed Volume Loss in AZ31 From Optical Corrosion Imprints and As‐Exposed Surface Topography

Advanced Intelligent Discovery, EarlyView.
How much material loss is concealed beneath a layer of corrosion products? This proof‐of‐concept study demonstrates how concealed volume loss is inferred from the optical appearance and as‐exposed surface topography of AZ31 corrosion imprints. By predicting postcleaning depth maps, a multimodal U‐Net model estimates hidden volume loss without chromic ...
Lars Dammann, Ci Song, Bahram Vaghefinazari, Tim Würger, Anna Lisitsyna, Shadi Albarqouni, Mikhail L. Zheludkevich, Sviatlana V. Lamaka, Christian Feiler   +8 more
wiley   +1 more source