Results 101 to 110 of about 1,581,517 (315)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Implementation of Patient Safety in Hospitals Related to Patient Satisfaction in 2023

open access: yesMedia Keperawatan Indonesia
The incidence of non-injury incidents at Panembahan Senopati Hospital, Bantul is still the highest case every year, this is still several non-injury incident cases of 45.5% in 2022, this case is because there are still nurses or health workers who have ...
Apriliya Tiyas Ningrum   +2 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

American Women's Hospitals Service photographs: Armenia, circa 1920, undated

open access: yes, 1922
The American Women's Hospitals (AWH) developed from the War Service Committee of the Medical Women's National Association (later, American Medical Women's Association (AMWA)) in 1917 to provide, register and finance American women physicians for war work;

core  

Survey-Based Studies of the Agility Construct in the Healthcare Sector: A Systematic Literature Review

open access: yesApplied Sciences
As a dynamic capability, agility has been extensively examined within manufacturing settings due to the industry’s dynamics and the imperative for rapid adaptation to unforeseen market changes.
Jorge Flavio Sarmiento Falla   +1 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

American Women's Hospitals Service photographs: France, circa 1920, 1948

open access: yes, 1917
The American Women's Hospitals (AWH) developed from the War Service Committee of the Medical Women's National Association (later, American Medical Women's Association (AMWA)) in 1917 to provide, register and finance American women physicians for war work;

core  

Patients\' Satisfaction in Hospitals of Iran: A systematic Review and Meta-Analysis

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2019
Background and Objectives: Patients' satisfaction is one of the important indicators for measuring healthcare quality in hospitals. The present study was performed aiming at determining the level of patients' satisfaction in hospitals of Iran.   Methods:
Parvaneh Esfahani, Fahze Nezamdust
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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