Results 111 to 120 of about 2,705,825 (317)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Developments in hospital management: a proposal for a new hospital management model for Malta [PDF]

open access: yes, 2002
The management of hospitals has changed considerably over the last two decades. The business processes and patient treatment regimes are unrecognisable from those of ten years ago.
Grech, Kenneth
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Assessment of Nurses Viewpoints on Patient Safety Culture in Amol Hospitals in Iran, 2012

open access: yesPreventive Care in Nursing and Midwifery Journal, 2015
Background and Objectives: Patient safety is the most vital indicator of hospital management. Ignorance of the patient safety may lead to an increase in hospital mortality rates due to medical errors.
Soghrat Phaghizadeh   +4 more
doaj  

The Hospice Friendly Hospitals Programme [PDF]

open access: yes, 2014
This report describes how care for people who die in Irish hospitals is planned and provided for; and how those processes evolved over the period 2007-2013. The report details a journey and we do not claim to have reached journey's end.
Kathy Walsh
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Hastalara Verilen Tıbbi Atıkların Kontrolü ve Sıfır Atık Yönetmeliği Eğitiminin Bilgi Düzeylerine Etkisi

open access: yesSağlık Bilimleri Üniversitesi Hemşirelik Dergisi
Giriş: Sağlık kurumlarında atıkların yönetimi, atık çeşitliliğinden dolayı birden fazla yönetmelik kapsamında yürütülebilmekte, bu durum da atık yönetimini zorlaştırabilmektedir.Amaç: Çalışma hastalara verilen tıbbi atıkların kontrolü ve sıfır atık ...
Sümeyra Demir   +6 more
doaj   +1 more source

Inferring Hospital Quality from Patient Discharge Records Using a Bayesian Selection Model [PDF]

open access: yes
This paper develops new econometric methods to estimate hospital quality and other models with discrete dependent variables and non-random selection. Mortality rates in patient discharge records are widely used to infer hospital quality.
Gautam Gowrisankaran, Robert J. Town
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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