Results 21 to 30 of about 3,477 (144)

CLEC14A correlates with neutrophil infiltration in hepatocellular carcinoma and mediates neutrophil recruitment across liver endothelial cells

The Journal of Pathology, EarlyView.
Abstract Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related deaths globally, and cases are predicted to rise dramatically over the next few years. Overcoming the immune microenvironment in HCC remains a challenge, and innate immune populations such as tumour‐associated neutrophils can potentially impair the success of immunotherapy ...
Joanne M O'Rourke, Dean Kavanagh, Ayla O'Keeffe, Kylie Savoye, Kaiyi Yang, Daniel A Patten, Catherine E Willoughby, Josep M Llovet, Georgiana Neag, Helen L Reeves, Peter W Hewett, Neena Kalia, Tahir Shah, Yuk Ting Ma, Kelly Hunter, Joe Flint, Jack L McMurray, Owen Cain, Fabian Spill, Derek A Mann, Amy J Naylor, Victoria Heath, Christopher J Weston, Roy Bicknell, Shishir Shetty   +24 more
wiley   +1 more source

Mothers against the natural order: Gender representations and desertion of identities in the drama of disinheriting a son in eighteenth‐century Barcelona  

Gender &History, EarlyView.
ABSTRACT The disinheritance of a firstborn son accustomed to the privileges of exclusion has for centuries been a dramatic event for families, especially if the decision was taken by a woman, the son's own mother. Very few dared to do so, because it symbolised a break with the notion of virtuous, compassionate motherhood; it represented a failure to be
Mariela Fargas Peñarrocha
wiley   +1 more source

Phenotyping Preeclampsia Using Unsupervised Machine Learning: A Prospective Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To explore clinically meaningful phenotypes of preeclampsia using unsupervised machine learning. Design Prospective cohort study. Setting BCNatal, a tertiary maternal‐foetal medicine centre (Barcelona, Spain). Population A total of 482 pregnant women diagnosed with preeclampsia between August 2013 and April 2024.
Ohad Houri, Lina Youssef, Francesca Crovetto, Maria Borrell, Maddalena Crimella, Maria Giulia Ferrante, Rommy H. Novoa, Irene Casas, Noelia Encabo, Leticia Benitez, Marta Larroya, Anna Peguero, Eva Meler, Sara Castro‐Barquero, Bart Bijnens, Francesc Figueras, Eduard Gratacos, Gabriel Bernardino, Fàtima Crispi   +18 more
wiley   +1 more source

Anatomical–Motor Level Discrepancy in Prenatal Diagnosis of Open Spinal Dysraphism: A 12‐Year Retrospective Observational Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objectives To quantify the discrepancy between anatomical and motor levels in foetuses with open spinal dysraphism and identify prenatal factors associated with this difference. We also examined associations between anatomical level and ultrasound findings. Design Retrospective observational study.
Silvia Arévalo, Elena Moreno, Mar Meléndez, Carlos Giné, Carlota Rodó, Alba Casellas, Alba Farràs, Manel Mendoza, Nerea Maiz   +8 more
wiley   +1 more source

Scaffold‐free three‐dimensional culture of chronic lymphocytic leukaemia preserves B–T‐cell cross‐talk and enables drug response profiling

British Journal of Haematology, EarlyView.
Summary Chronic lymphocytic leukaemia (CLL) presents a complex biological and clinical landscape, strongly influenced by the tumour microenvironment (TME). To better capture this heterogeneity, we have developed patient‐derived lymphoma spheroids from CLL samples (CLL‐PDLS), which recapitulate the cross‐talk between malignant cells and the autologous ...
Heribert Playa‐Albinyana, Ariadna Giró, Juan A. Piñeyroa, Ferran Araujo‐Ayala, Cèlia Dobaño‐López, Sara Otín‐Sánchez, Elías Campo, Christine Bezombes, Patricia Pérez‐Galán, Dolors Colomer   +9 more
wiley   +1 more source

Proteomic profile of CSF obtained at the time of diagnosis determines amyotrophic lateral sclerosis progression and survival: CXCL7 levels in disease prognosis and survival

Brain Pathology, EarlyView.
Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira, Yaiza López‐Sampere, Pol Mengod‐Soler, Mario Peña‐Fonteboa, Carla Marco, Alejandro Caravaca‐Puchades, Raúl Domínguez, Juan Francisco Vázquez‐Costa, Enrique Santamaría, Joaquín Fernández‐Irigoyen, María J. Colomina, Isabel León Moreno, Antonio Martínez Yélamos, Sergio Martínez Yélamos, Gabriel Santpere, Elia Obis, Manuel Portero‐Otín, Gerard Piñol‐Ripoll, Mónica Povedano, Pol Andrés‐Benito   +19 more
wiley   +1 more source

Evaluating Guideline Adherence in Gemini‐Powered Dental Trauma Workflows: Standalone Gemini Chat vs. Document‐Grounded NotebookLM

Dental Traumatology, EarlyView.
ABSTRACT Aim The aim of this study was to compare the accuracy and inter‐account consistency of two Google Gemini–powered, user‐facing workflows for dental trauma decision support: standalone Gemini chat and NotebookLM, a document‐grounded workflow that generates responses grounded in uploaded European Society of Endodontology and International ...
Nicolás Dufey‐Portilla, Francesc Abella Sans, Fernando Duran‐Sindreu, Maria Teresa Salagaray, Venkateshbabu Nagendrababu, Paul V. Abbott, Liran Levin, Marc Garcia‐Font   +7 more
wiley   +1 more source

Awareness and early implementation of the European AIDS Clinical Society Guidance on statin use in HIV for the primary prevention of cardiovascular disease: A cross‐sectional survey of HIV clinicians in Europe

HIV Medicine, EarlyView.
Abstract Objectives Cardiovascular disease (CVD) is a major comorbidity and leading cause of morbidity and mortality in people with HIV (PWH). The REPRIEVE trial demonstrated that statin therapy significantly reduces cardiovascular events in PWH, prompting updated recommendations from major international societies.
Jasmini Alagaratnam, Abiu Sempere, Susanne Dam Nielsen, Esteban Martinez   +3 more
wiley   +1 more source

Mapping the Drivers of Engagement in Mentorship in Nursing Clinical Practicums: A Network Analysis

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To map factors influencing nurses' engagement in clinical mentorship in nursing education and explore their interactions using network analysis. Design Observational cross‐sectional study employing an online survey from July 2024 to May 2025.
Eva Padrosa, Aggie Núñez‐Doyle, Raquel Ayuso‐Margañon, Rosa Rifà‐Ros, Montse Sanclemente‐Dalmau, Carlota Alcover, Anna Martín‐Arribas, Ariadna Graells‐Sans, Miriam Rodríguez‐Monforte   +8 more
wiley   +1 more source

Three‐Dimensional Effects of Two Minimally Invasive Surgically Assisted Rapid Palatal Expansion Techniques

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT Objective This study evaluated, in three dimensions, the skeletal effects of two minimally invasive bone‐anchored techniques for surgically assisted palatal expansion, with and without pterygomaxillary disjunction (PD) and nasal septum disinsertion (NSD). Materials and Methods Thirty‐nine patients were retrospectively selected from two centres
Bibiana Mello da Rosa, Orion Luiz Haas Jr., Rubens Martins Bastos, Rogério Belle de Oliveira, Federico Hernández‐Alfaro, Adaia Valls‐Ontañón, Luciane Macedo de Menezes   +6 more
wiley   +1 more source