Results 131 to 140 of about 136,526 (254)

The ATM Kinase Inhibitor AZD0156 Is a Potent Inhibitor of Plasmodium Phosphatidylinositol 4‐Kinase (PI4Kβ) and Is an Attractive Candidate for Medicinal Chemistry Optimization Against Malaria

Angewandte Chemie, EarlyView.
AZD0156, an ATM kinase inhibitor in clinical development, shows promising multistage antiplasmodial activity by targeting Plasmodium falciparum phosphatidylinositol 4‐kinase (PfPI4Kβ). With an improved specificity profile relative to other PfPI4Kβ inhibitors and moderate efficacy in a P.
John G. Woodland, Dina Coertzen, Kathryn J. Wicht, Virginia Franco Hidalgo, Charisse Flerida A. Pasaje, Luiz C. Godoy, Tarrick Qahash, Mmakwena M. Mmonwa, Godwin A. Dziwornu, Lynn Wambua, Sarah Harries, Constance M. Korkor, Mathew Njoroge, Liezl Krugmann, Dale Taylor, Meta Leshabane, Henrico Langeveld, Tayla Rabie, Janette Reader, Mariëtte van der Watt, Nelius Venter, Erica Erlank, Ayesha S. Aswat, Lizette L. Koekemoer, Tomas Yeo, Jin H. Jeon, David A. Fidock, Francisco Javier Gamo, Sergio Wittlin, Jacquin C. Niles, Manuel Llinas, Lauren B. Coulson, Lyn‐Marié Birkholtz, Kelly Chibale   +33 more
wiley   +2 more sources

The Impact of Temperature on Host-Parasite Interactions and Metabolomic Profiles in the Marine Diatom Coscinodiscus granii. [PDF]

Plants (Basel)
O'Niel RA, Pohnert G, Vallet M.
europepmc   +1 more source

News Insights into the Host-Parasite Interactions of Amyloodiniosis in European Sea Bass: A Multi-Modal Approach. [PDF]

Pathogens, 2022
Massimo M, Volpatti D, Galeotti M, Bron JE, Beraldo P.   +4 more
europepmc   +1 more source

Investigating Social Immunity in Swarming Locusts via a Triple Animal–Robot–Pathogen Hybrid Interaction

Advanced Intelligent Systems, EarlyView.
This study explores social immunity in gregarious locusts using a groundbreaking animal–robot–pathogen interaction model. By comparing locust responses to biomimetic agents mimicking healthy and infected individuals, significant behavioral changes are revealed.
Donato Romano, Cesare Stefanini
wiley   +1 more source

Host-Parasite Interactions in Toxoplasma gondii-Infected Cells: Roles of Mitochondria, Microtubules, and the Parasitophorous Vacuole. [PDF]

Int J Mol Sci
Barik S, Andrews J.
europepmc   +1 more source

Profiling the serum proteome during Schistosoma mansoni infection in the BALB/c mice: A focus on the altered lipid metabolism as a key modulator of host-parasite interactions. [PDF]

Front Immunol, 2022
Gonçalves-Silva G, Vieira LGMDS, Cosenza-Contreras M, Souza AFP, Costa DC, Castro-Borges W.   +5 more
europepmc   +1 more source

Multi‐Module Micro/Nanorobots for Biomedical and Environmental Remediation Applications

Advanced Intelligent Systems, EarlyView.
Multi‐module microrobots (MNRs) have overcome the limitations of single‐module systems by integrating components such as propeller, actuator, manipulator, and imaging modalities. They show promise in biomedical applications, such as targeted drug delivery and tissue repair, as well as in environmental remediation, including pollutant removal.
Bairong Zhu, Amar Salehi, Lei Xu, Wei Yuan, Tingting Yu   +4 more
wiley   +1 more source

Testing the evolutionary drivers of malaria parasite rhythms and their consequences for host-parasite interactions. [PDF]

Evol Appl
Holland JG, Prior KF, O'Donnell AJ, Reece SE.   +3 more
europepmc   +1 more source

Host-parasite interactions in infections due to Entamoeba histolytica: A tale of known and unknown.

Trop Parasitol, 2022
Singh A, Banerjee T.
europepmc   +1 more source

Dual RNA Sequencing Meta-analysis in Plasmodium Infection Identifies Host-Parasite Interactions. [PDF]

mSystems, 2021
Mukherjee P, Burgio G, Heitlinger E.
europepmc   +1 more source