Transplantation of medial ganglionic eminence (MGE) interneuron progenitors into APP/PS1 cortices restored the slow oscillation characteristic of Alzheimer's disease. Donor cells survived, migrated, and matured into functional GABAergic interneurons, forming synaptic connections.
Shinya Yokomizo +16 more
wiley +1 more source
Host-parasite interactions and mechanisms of infection in amebiasis [PDF]
Amebiasis is caused by E. histolytica, which is the only species pathogenic in humans, while the pathogeneicity of E. dispar and E. moshkovskii is still unclear.
Suriptiastuti
doaj
Parasite-host interactions between Protocalliphora Spp. (Diptera: Calliphoridae) and tree swallows Tachycineta bicolor [PDF]
Daniel R. Williams
openalex +1 more source
Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance
Precision engineering of plant NLR immune receptors enables rational design of enhanced pathogen resistance through mismatched pairing, domain swapping, and targeted mutagenesis. These approaches achieve multi‐fold expansion in recognition breadth while minimizing autoimmunity risks and fitness penalties.
Vinit Kumar +7 more
wiley +1 more source
Fasciolosis: pathogenesis, host-parasite interactions, and implication in vaccine development. [PDF]
Flores-Velázquez LM +9 more
europepmc +1 more source
Studies on Biology, Seed dispersal and Host interaction of Dendrophthoe falcata (L.f.) Etting. - A stem parasite of Mangifera indica L. (Mango) [PDF]
Subhashini Kuramana +2 more
openalex +1 more source
TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng +9 more
wiley +1 more source
A review of the taxonomic diversity, host-parasite interactions, and experimental research on chytrids that parasitize diatoms. [PDF]
Danz A, Quandt CA.
europepmc +1 more source
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan +16 more
wiley +1 more source
Proteomics Applications in <i>Toxoplasma gondii</i>: Unveiling the Host-Parasite Interactions and Therapeutic Target Discovery. [PDF]
Deng B, Vanagas L, Alonso AM, Angel SO.
europepmc +1 more source

