Results 1 to 10 of about 4,950,424 (307)

Classification and prediction of Mycobacterium Avium subsp. Paratuberculosis (MAP) shedding severity in cattle based on young stock heifer faecal microbiota composition using random forest algorithms

Animal Microbiome, 2021
Background Bovine paratuberculosis is a devastating infectious disease caused by Mycobacterium avium subsp. paratuberculosis (MAP). The development of the paratuberculosis in cattle can take up to a few years and vastly differs between individuals in ...
Alexander Umanets, Annemieke Dinkla, Stephanie Vastenhouw, Lars Ravesloot, Ad P. Koets   +4 more
doaj   +1 more source

Efficient Inhibition of HIV Using CRISPR/Cas13d Nuclease System

Viruses, 2021
Recently discovered Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas13 proteins are programmable RNA-guided ribonucleases that target single-stranded RNA (ssRNA).
Hoang Nguyen, Hannah Wilson, Sahana Jayakumar, Viraj Kulkarni, Smita Kulkarni   +4 more
doaj   +1 more source

Changes in Fecal Carriage of Extended-Spectrum β-Lactamase Producing Enterobacterales in Dutch Veal Calves by Clonal Spread of Klebsiella pneumoniae

Frontiers in Microbiology, 2022
This study aimed to characterize the changes in fecal carriage of Extended-Spectrum β-Lactamase (ESBL) producing Enterobacterales (ESBL-PE) in a single Dutch veal calves.
Teresita d.J. Bello Gonzalez, Arie Kant, Quillan Dijkstra, Francesca Marcato, Kees van Reenen, Kees T. Veldman, Michael S. M. Brouwer   +6 more
doaj   +1 more source

Resistance and Susceptibility Immune Factors at Play during Mycobacterium tuberculosis Infection of Macrophages

Pathogens, 2022
Tuberculosis (TB), caused by infection with Mycobacterium tuberculosis (M.tb), is responsible for >1.5 million deaths worldwide annually. Innate immune cells, especially macrophages, are the first to encounter M.tb, and their response dictates the course
Jan D. Simper, Esteban Perez, Larry S. Schlesinger, Abul K. Azad   +3 more
doaj   +1 more source

Experimental Chlamydia gallinacea infection in chickens does not protect against a subsequent experimental Chlamydia psittaci infection

Veterinary Research, 2021
Chlamydia psittaci was considered the predominant chlamydial species in poultry until Chlamydia gallinacea was discovered in 2009. C. psittaci is a zoonotic obligate intracellular bacterium reported in more than 465 bird species including poultry.
Marloes Heijne, Jeanet van der Goot, Herma Buys, Annemieke Dinkla, Hendrik Jan Roest, Lucien van Keulen, Ad Koets   +6 more
doaj   +1 more source

Aid or Antagonize: Nuclear Long Noncoding RNAs Regulate Host Responses and Outcomes of Viral Infections

Cells, 2023
Long noncoding RNAs (lncRNAs) are transcripts measuring >200 bp in length and devoid of protein-coding potential. LncRNAs exceed the number of protein-coding mRNAs and regulate cellular, developmental, and immune pathways through diverse molecular ...
Viraj Kulkarni, Sahana Jayakumar, Mahesh Mohan, Smita Kulkarni   +3 more
doaj   +1 more source

COVID-19 Pandemic and Vaccines Update on Challenges and Resolutions

Frontiers in Cellular and Infection Microbiology, 2021
The coronavirus disease (COVID-19) is caused by a positive-stranded RNA virus called severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), belonging to the Coronaviridae family.
Wajihul Hasan Khan, Wajihul Hasan Khan, Zohra Hashmi, Aditya Goel, Razi Ahmad, Kanisha Gupta, Nida Khan, Iqbal Alam, Faheem Ahmed, Mairaj Ahmed Ansari   +9 more
doaj   +1 more source

No More Monkeying Around: Primate Malaria Model Systems are Key to Understanding Plasmodium vivax Liver-Stage Biology, Hypnozoites, and Relapses

Frontiers in Microbiology, 2015
Plasmodium vivax is a human malaria parasite responsible for significant morbidity worldwide and potentially death. This parasite possesses formidable liver-stage biology that involves the formation of dormant parasites known as hypnozoites.
Chester J Joyner, Chester J Joyner, John W Barnwell, John W Barnwell, Mary R Galinski, Mary R Galinski, Mary R Galinski   +6 more
doaj   +1 more source

Integrative analysis associates monocytes with insufficient erythropoiesis during acute Plasmodium cynomolgi malaria in rhesus macaques

Malaria Journal, 2017
Background Mild to severe anaemia is a common complication of malaria that is caused in part by insufficient erythropoiesis in the bone marrow. This study used systems biology to evaluate the transcriptional and alterations in cell populations in the ...
Yan Tang, Chester J. Joyner, Monica Cabrera-Mora, Celia L. Saney, Stacey A. Lapp, Mustafa V. Nural, Suman B. Pakala, Jeremy D. DeBarry, Stephanie Soderberg, the MaHPIC Consortium, Jessica C. Kissinger, Tracey J. Lamb, Mary R. Galinski, Mark P. Styczynski   +13 more
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Correction to: Integrative analysis associates monocytes with insufficient erythropoiesis during acute Plasmodium cynomolgi malaria in rhesus macaques

Malaria Journal, 2017
After publication of the article [1], it was brought to our attention that several symbols were missing from Fig. 1, including some cited in the figure’s key.
Yan Tang, Chester J. Joyner, Monica Cabrera-Mora, Celia L. Saney, Stacey A. Lapp, Mustafa V. Nural, Suman B. Pakala, Jeremy D. DeBarry, Stephanie Soderberg, the MaHPIC Consortium, Jessica C. Kissinger, Tracey J. Lamb, Mary R. Galinski, Mark P. Styczynski   +13 more
doaj   +1 more source