Results 61 to 70 of about 4,950,424 (307)

Co-option of Plasmodium falciparum PP1 for egress from host erythrocytes

Nature Communications, 2020
Plasmodium protein phosphatase PP1 is essential for the asexual proliferation of malaria parasites. Here the authors show that PP1 regulates egress of parasites from host red blood cells, integrating parasite intrinsic pathways with environmental signals
Aditya S. Paul, Alexandra Miliu, Joao A. Paulo, Jonathan M. Goldberg, Arianna M. Bonilla, Laurence Berry, Marie Seveno, Catherine Braun-Breton, Aziz L. Kosber, Brendan Elsworth, Jose S. N. Arriola, Maryse Lebrun, Steven P. Gygi, Mauld H. Lamarque, Manoj T. Duraisingh   +14 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

The integrated concept of disease resistance; a new view including horizontal and vertical resistance in plants [PDF]

, 1977
Horizontal, uniform, race-non-specific or stable resistance can be discerned according to Van der Plank, from vertical, differential, race-specific or unstable resistance by a test in which a number of host genotypes (cultivars or clones) are tested ...
Zadoks, J.C., Parlevliet, J.E.
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

In Planta Transcriptome and Proteome Profiles of Spongospora subterranea in Resistant and Susceptible Host Environments Illuminates Regulatory Principles Underlying Host–Pathogen Interaction [PDF]

, 2021
Spongospora subterranea is an obligate biotrophic pathogen, causing substantial economic loss to potato industries globally. Currently, there are no fully effective management strategies for the control of potato diseases caused by S. subterranea.
David S. Nichols, Wilson, Calum R., Nichols, David S., Balotf, Sadegh, Calum R. Wilson, Wilson, Richard, Tegg, Robert S., Robert S. Tegg, Sadegh Balotf, Richard Wilson   +9 more
core   +1 more source

Multiphoton imaging of host‐pathogen interactions

Biotechnology Journal, 2009
AbstractStudying the events that occur when a pathogen comes into contact with its host is the basis of the field of infection biology. Over the years, work in this area has revealed many facets of the infection process, including attachment, invasion and colonization by the pathogen, and of the host responses, such as the triggering of the immune ...
Melican, Keira, Richter-Dahlfors, Agneta
openaire   +3 more sources

Unraveling Caspofungin Resistance in Cryptococcus neoformans

mBio, 2021
Cryptococcus ...
Nicolas Papon, Gustavo H. Goldman
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Genome-wide analysis reveals loci encoding anti-macrophage factors in the human pathogen burkholderia pseudomallei K96243 [PDF]

, 2010
Burkholderia pseudomallei is an important human pathogen whose infection biology is still poorly understood. The bacterium is endemic to tropical regions, including South East Asia and Northern Australia, where it causes melioidosis, a serious disease ...
Wilkinson Paul A., Dowling, Andrea J., Matthew T G Holden, Richard W. Titball, Nicholas R. Waterfield, Paul A Wilkinson, Titball, Richard W., Quail, MA, Bentley Stephen D., Holden Matthew T. G., Richard W Titball, Bentley, SD, Julia Reger, Quail, Michael A., Waterfield Nicholas R., Stephen D. Bentley, Waterfield, NR, Andrea J Dowling, Stephen D Bentley, Wilkinson, Paul A., Bentley, Stephen D., Holden, Matthew T. G., ffrench-Constant, Richard H., ffrench-Constant Richard H., ffrench-Constant, Richard, Richard H. ffrench-Constant, Paul A. Wilkinson, Matthew T. G. Holden, Michael A. Quail, Michael A Quail, Waterfield, Nicholas R., Dowling Andrea J., Reger, J, Titball Richard W., Nicholas R Waterfield, Reger, Julia, Quail Michael A., Andrea J. Dowling, Andrea J. Dowling, Richard H Ffrench-Constant, Dowling, AJ, Holden, Matthew, Wilkinson, PA, Reger Julia   +43 more
core   +1 more source

ER stress selects for Candida auris survivors with acquired fluconazole resistance and caspofungin tolerance

Frontiers in Microbiology
Exposure to endoplasmic reticulum (ER) stress can drive the emergence of antifungal resistance in pathogenic fungi, but the underlying mechanisms remain poorly understood.
Feng Yang, Liuliu Sun, Hao Li, Ting Fang, Qinli Guo, Nan Chen, Yuanying Jiang   +6 more
doaj   +1 more source