Results 31 to 40 of about 4,941,149 (295)
Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul +13 more
wiley +1 more source
An attractor for the dynamical state of the intracluster medium
Galaxy clusters provide us with important information about the cosmology of our universe. Observations of the X-ray radiation or of the SZ effect allow us to measure the density and temperature of the hot intergalactic medium between the galaxies in a ...
Barber +16 more
core +1 more source
Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan +6 more
wiley +1 more source
Benefits of host genetic diversity for resistance to infection depend on parasite diversity [PDF]
Host populations with high genetic diversity are predicted to have lower levels of infection prevalence. This theory assumes that host genetic diversity results in variation in susceptibility and that parasites exhibit variation in infectivity. Empirical
Ebert, D., Ganz, H.
core +1 more source
ABSTRACT Background Gastrointestinal graft‐versus‐host disease (GI GVHD) following hematopoietic stem cell transplant is typically managed with medical therapy, but surgery and angioembolization may be warranted in selected cases with life‐threatening complications.
Gaia Brunetti +12 more
wiley +1 more source
Host and symbiont genetic contributions to fitness in a Trichogramma-Wolbachia symbiosis. [PDF]
The fitness effects associated with Wolbachia infection have wide-ranging ecological and evolutionary consequences for host species. How these effects are modulated by the relative influence of host and Wolbachia genomes has been described as a balancing
Nunney, Leonard +3 more
core +2 more sources
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich +5 more
wiley +1 more source
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta +6 more
wiley +1 more source
In this article, we analyse the intellectual trajectory of André Pinto Rebouças (1838-1898) between 1870 and 1888, and how he problematised the relation between education, technology, and social reform.
Silva Wladimir Barbosa da +1 more
doaj +1 more source
The Host Galaxy of GRB 060505: Host ISM Properties
We investigate the ISM environment of GRB 060505. Using optical emission-line diagnostic ratios, we compare the ISM properties of the GRB 060505 host region with the hosts of unambiguous long- and short-duration GRBs.
Emily M. Levesque +3 more
core +1 more source

