Results 51 to 60 of about 2,883,220 (256)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
HoST, 2019 By focusing on the books of popularization of science and technology published by Gradiva this research aims at understanding the mechanisms and strategies to bring science and technology to a broader audience in Portugal, after 1974, the year of the ...
Navalhas Inês N.
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Host-Parasite list of cartilaginous fish
, 2022 I combined data from three publicly available datasets, namely Shark Reference (https://shark-references.com/) (Pollerspöck & Straube, 2020), World Register of Marine Species (WoRMS) (www.marinespecies.org) (Horton et al., 2019) and the Elasmobranch Host
Thomas Morris (11798483)
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Public Electricity Supply in Portuguese Guinea, 1930-1974
HoSTGuinea-Bissau has a chronically underperforming electricity sector that fails to provide most of the population outside of the capital, Bissau, with access to electricity – nowadays considered a basic human need.
Stoppok Manfred
doaj +1 more source
Host-targeting antivirals for flaviviruses.
, 2022 Host-targeting antivirals for flaviviruses.
Vinod RMT Balasubramaniam (12475307) +3 more
core +1 more source
The genetics of host adaptation in the parasitic plant Striga hermonthica [PDF]
, 2013 The obligately outbreeding root hemiparasite Striga hermonthica (Orobanchaceae)is a serious threat to subsistence agriculture in sub-Saharan Africa. Resistance to this parasite in its crop hosts, such as rice, sorghum and maize, is not common, and the ...
Pescott, Oliver
core +4 more sources
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
The Social Evolving: Sociogenomics on the Wings of Social Insects
HoST, 2019 This paper excavates the epistemological and ontological foundations of a rapidly emerging field called sociogenomics in relation to the development of social insects as models of social behavior.
Suryanarayanan Sainath
doaj +1 more source