Results 221 to 230 of about 3,640,353 (386)

Tunable Synthetic Hydrogel Modulates Hepatic Lineage Specification of Human Liver Organoid

Advanced Functional Materials, EarlyView.
In this study, a synthetic hydrogel is reported that supports the formation of hiPSC‐derived human liver organoids (HLOs). Hepatic lineage specification can be modulated via conjugation of RGD peptide to hydrogel: RGD‐conjugated hydrogels promote cholangiocyte differentiation, whereas RGD‐free hydrogels favor hepatocyte commitment of HLO cells.
Lei Wang, Lasse Riediger, Qi Rao, Xun Xu, Yan Nie, Yiduo Zhou, Junyao Zhang, Peng Tang, Weiwei Wang, Frank Tacke, Adrien Guillot, Ludovic Vallier, Irene Talon, Wenzhong Li, Yi‐An Yang, Rainer Haag, Nan Ma   +16 more
wiley   +1 more source

Cryomazine concentration and host type effects on the biology of the southern cowpea weevil Callosobruchus maculatus F. [PDF]

, 2011
Abdu Al Mekhlafi Fahd, Ashraf Mashaly, Ahmed Wadaan Mohamed, M Al Mallah Nazar   +3 more
openalex   +1 more source

The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease.

Biology of Blood and Marrow Transplantation, 2017
K. Cooke, L. Luznik, S. Sarantopoulos, F. Hakim, M. Jagasia, D. Fowler, M. V. D. van den Brink, J. Hansen, R. Parkman, D. Miklos, P. Martin, S. Paczesny, G. Vogelsang, S. Pavletic, J. Ritz, K. Schultz, B. Blazar   +16 more
semanticscholar   +1 more source

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

Advanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer, Joanna M. Sadowska, Nadia Roumans, Christian Plank, Christopher H. Evans, Fergal J. O'Brien, Martijn van Griensven, Elizabeth R. Balmayor   +7 more
wiley   +1 more source

PREDICTIVE SYSTEMS BIOLOGY APPROACH TO BROAD-SPECTRUM, HOST-DIRECTED DRUG TARGET DISCOVERY IN INFECTIOUS DISEASES [PDF]

, 2012
Ramon M. Felciano, Sina Bavari, Daniel R. Richards, Jean-Noël Billaud, Travis K. Warren, Rekha G. Panchal, A. Krämer   +6 more
openalex   +1 more source

Highly Active Air Electrode with Enhanced Proton Conduction via Isovalent Doping in a Layered Perovskite for Reversible Protonic Ceramic Cells

Advanced Functional Materials, EarlyView.
A Ni‐doped PBSCN20 air electrode is proposed as a promising air electrode material for reversible protonic ceramic cells. An isovalent doping significantly facilitates oxygen vacancy formation and proton uptake while simultaneously reducing the energy barrier for proton migration.
Jiwon Yun, Hyeongsik Shin, Seungchan Kim, Boseok Seong, Seongjae Lee, Kyeounghak Kim, Sun Hee Choi, Sihyuk Choi   +7 more
wiley   +1 more source

LncRNAs harbouring regulatory motifs within repeat elements modulate immune response towards COVID‐19 disease severity and clinical outcomes

Clinical and Translational Medicine, 2022
Partha Chattopadhyay, Pallavi Mishra, Kriti Khare, Aanchal Yadav, Priyanka Mehta, Sheeba Saifi, Aparna Swaminathan, Priti Devi, Shaista Parveen, Akansha Tyagi, Vinita Jha, Bansidhar Tarai, Sujeet Jha, Sandeep Budhiraja, Jitendra Narayan, Rajesh Pandey   +15 more
doaj   +1 more source

Physiological and ecological hosts of Popenaias popeii (Bivalvia: Unionidae): laboratory studies identify more hosts than field studies. Freshwater Biology, 57, 1854–1864. DOI: 10.1111/j.1365‐2427.2012.02844.x [PDF]

, 2012
Todd Levine, Brian K. Lang, David J. Berg   +2 more
openalex   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source