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SARS-CoV-2 Biology and Host Interactions [PDF]
Nature Reviews MicrobiologyThe zoonotic emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the ensuing coronavirus disease 2019 (COVID-19) pandemic have profoundly affected our society. The rapid spread and continuous evolution of new SARS-CoV-2 variants continue to threaten global public health.
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Inorganic polyphosphate in host and microbe biology
Trends in Microbiology, 2021Inorganic polyphosphate (polyP) is produced by both bacteria and their eukaryotic hosts, and it appears to play multiple important roles in the interactions between those organisms. However, the detailed mechanisms of how polyP synthesis is regulated in bacteria, and how it influences both bacterial and host biology, remain largely unexplored.
Marvin Q, Bowlin, Michael J, Gray
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Mycobacterium tuberculosis Biology, Pathogenicity and Interaction With the Host
Nature Reviews MicrobiologySince the release of the first Mycobacterium tuberculosis genome in 1998, major advances have been made in understanding the biology of this pathogen, the leading infectious cause of death in modern human history. In this Review, we outline the physiological and metabolic features thought to underpin the survival, evasion and subversion strategies ...
Digby F Warner +2 more
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Drug Discovery Today, 2006
Unlike traditional biological research that focuses on a small set of components, systems biology studies the complex interactions between a large number of genes, proteins and other elements of biological networks and systems. Host-pathogen systems biology examines the interactions between the components of two distinct organisms, either a microbial ...
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Unlike traditional biological research that focuses on a small set of components, systems biology studies the complex interactions between a large number of genes, proteins and other elements of biological networks and systems. Host-pathogen systems biology examines the interactions between the components of two distinct organisms, either a microbial ...
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The Biology of Viroid-Host Interactions
Annual Review of Phytopathology, 2009Viroids are single-stranded, circular, and noncoding RNAs that infect plants. They replicate in the nucleus or chloroplast and then traffic cell-to-cell through plasmodesmata and long distance through the phloem to establish systemic infection. They also cause diseases in certain hosts.
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Schistosomiasis: Host-Pathogen Biology
Clinical Infectious Diseases, 1982Schistosomes are helminths of the class Trematoda that alternate generations, with a sexual phase in definitive mammalian hosts and an asexual phase in intermediate snail hosts. In humans, these blood flukes reside in the mesenteric and vesical venules. They have a life span of many years and daily produce large numbers of eggs, which must traverse the
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Biology of host-macroparasite associations
1991Abstract Many important diseases of humans, particularly in tropical and subtropical regions, arise from infection by macroparasites or metazoan (multicellular) organisms. The major parasites belong to the helminth and arthropod groups, and include flukes (the trematodes), tapeworms (the cestodes), nematodes, lice, fleas, and ticks ...
Roy M Anderson, Robert M May
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Giardiasis: Host-Pathogen Biology
Clinical Infectious Diseases, 1982Giardiasis is the most common waterborne diarrheal disease in the United States and is highly prevalent throughout the world. The clinical spectrum of disease ranges from asymptomatic infection to persistent severe malabsorption. The precise interaction between Giardia and its human host remains conjectural because of the paucity of published studies ...
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