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Inorganic polyphosphate in host and microbe biology

Trends in Microbiology, 2021
Inorganic polyphosphate (polyP) is produced by both bacteria and their eukaryotic hosts, and it appears to play multiple important roles in the interactions between those organisms. However, the detailed mechanisms of how polyP synthesis is regulated in bacteria, and how it influences both bacterial and host biology, remain largely unexplored.
Marvin Q, Bowlin, Michael J, Gray
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Host–Pathogen Systems Biology

Drug Discovery Today, 2006
Unlike traditional biological research that focuses on a small set of components, systems biology studies the complex interactions between a large number of genes, proteins and other elements of biological networks and systems. Host-pathogen systems biology examines the interactions between the components of two distinct organisms, either a microbial ...
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The Biology of Viroid-Host Interactions

Annual Review of Phytopathology, 2009
Viroids are single-stranded, circular, and noncoding RNAs that infect plants. They replicate in the nucleus or chloroplast and then traffic cell-to-cell through plasmodesmata and long distance through the phloem to establish systemic infection. They also cause diseases in certain hosts.
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Schistosomiasis: Host-Pathogen Biology

Clinical Infectious Diseases, 1982
Schistosomes are helminths of the class Trematoda that alternate generations, with a sexual phase in definitive mammalian hosts and an asexual phase in intermediate snail hosts. In humans, these blood flukes reside in the mesenteric and vesical venules. They have a life span of many years and daily produce large numbers of eggs, which must traverse the
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Giardiasis: Host-Pathogen Biology

Clinical Infectious Diseases, 1982
Giardiasis is the most common waterborne diarrheal disease in the United States and is highly prevalent throughout the world. The clinical spectrum of disease ranges from asymptomatic infection to persistent severe malabsorption. The precise interaction between Giardia and its human host remains conjectural because of the paucity of published studies ...
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Amebiasis: Host-Pathogen Biology

Clinical Infectious Diseases, 1982
Invasive amebiasis caused by Entamoeba histolytica, and particularly amebic liver abscess, is a major public health problem in Mexico and some other countries because of the high incidence and mortality of this disease. This paper first discusses the pathogenic effect of E.
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Biology of host-macroparasite associations

1991
Abstract Many important diseases of humans, particularly in tropical and subtropical regions, arise from infection by macroparasites or metazoan (multicellular) organisms. The major parasites belong to the helminth and arthropod groups, and include flukes (the trematodes), tapeworms (the cestodes), nematodes, lice, fleas, and ticks ...
Roy M Anderson, Robert M May
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Ascariasis: Host-Pathogen Biology

Clinical Infectious Diseases, 1982
Ascaris lumbricoides is one of the most common intestinal parasites in humans. Daily global contamination of the soil by A. lumbricoides eggs is enormous (approximately 9 x 10(14) eggs/day). Physical factors, particularly temperature and moisture, are critical in determining the maturation of eggs to the infective stage and their survival. Transmission
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The Biology of Cystitis: Host and Bacterial Factors

Annual Review of Medicine, 1999
Cystitis is caused by a relatively small number of bacterial species. To colonize and grow in the urinary tract, these organisms have developed and acquired special properties (virulence factors) that allow them to overcome the defences of the urinary tract, particularly clearance by urine flow.
M, Sussman, D L, Gally
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Malaria: Host-Pathogen Biology

Clinical Infectious Diseases, 1982
The development of resistance to insecticides by anopheline mosquito vectors of malaria and of resistance to drugs by Plasmodium falciparum pose new challenges for malaria control programs. The establishment of methods for the continuous cultivation in vitro of plasmodia provided an important new tool for research into the cellular biology and ...
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