Results 1 to 10 of about 195,419 (261)
Helper-Like Type-1 Innate Lymphoid Cells in Inflammatory Bowel Disease
Frontiers in Immunology, 2022 Inflammatory bowel disease (IBD) is an idiopathic condition characterized by chronic relapsing inflammation in the intestine. While the precise etiology of IBD remains unknown, genetics, the gut microbiome, environmental factors, and the immune system ...
Diana Coman +3 more
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Candidalysins Are a New Family of Cytolytic Fungal Peptide Toxins
mBio, 2022 Candidalysin is the first cytolytic peptide toxin identified in any human fungal pathogen. Candidalysin is secreted by Candida albicans and is critical for driving infection and host immune responses in several model systems.
Jonathan P. Richardson +18 more
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Frontiers in Molecular Biosciences, 2021 Bacterial extracellular vesicles (EVs) have a vital role in bacterial pathogenesis. However, to date, the small RNA-cargo of EVs released by the opportunistic pathogen Staphylococcus aureus has not been characterized.
Bishnu Joshi +10 more
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Journal of Water and Health, 2021 Laguna Lake is the largest inland freshwater body in the Philippines. Although it is classified to be usable for agricultural and recreational purposes by the country's Department of Environment and Natural Resources (DENR), studies looking at lake ...
Joseth Jermaine M. Abello +6 more
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Microorganisms, 2023 Sources of fecal contamination in Laguna Lake, Philippines, were identified using a library-independent microbial source tracking method targeting host-associated Bacteroides 16S rDNA-based markers. Water samples from nine lake stations were assessed for
Gicelle T. Malajacan +3 more
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Albumin Neutralizes Hydrophobic Toxins and Modulates Candida albicans Pathogenicity
mBio, 2021 Albumin is the most abundant serum protein in humans. During inflammation, serum albumin levels decrease drastically, and low albumin levels are associated with poor patient outcome.
Sophie Austermeier +10 more
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Animals, 2023 Although antibiotic resistance emerges naturally, this process has been accelerated by the worldwide overuse and misuse of antibiotics. It is essential to find effective alternatives in the broiler industry to improve poultry health while maintaining ...
Ines Dieryck +8 more
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Candidalysin Is a Potent Trigger of Alarmin and Antimicrobial Peptide Release in Epithelial Cells
Cells, 2020 Host released alarmins and antimicrobial peptides (AMPs) are highly effective as antifungal agents and inducers. Whilst some are expressed constitutively at mucosal tissues, the primary site of many infections, others are elicited in response to ...
Jemima Ho +5 more
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Abundance and diversity of resistomes differ between healthy human oral cavities and gut
Nature Communications, 2020 Antimicrobial resistance (AMR) represents a global health threat. Here, the authors analyse the oral and gut resistomes from metagenomes of diverse populations and find that the oral resistome harbours higher abundance but lower diversity of ...
Victoria R. Carr +7 more
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Microbiology Spectrum, 2022 Serine palmitoyltransferase catalyzes the first step of the sphingolipid biosynthesis. Recently, sphingolipid homeostasis has been connected to several human diseases, making serine palmitoyltransferases an interesting therapeutic target.
Sandra Hoefgen +6 more
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