Results 31 to 40 of about 195,419 (261)

Editorial: Microbial interactions across species: shaping pathogenesis, symbiosis, and ecosystem dynamics [PDF]

Frontiers in Microbiology
Jong Hyun Ham, Bryan Swingle, Gregg S. Pettis   +2 more
doaj   +2 more sources

Site-specific glycosylation regulates the form and function of the intermediate filament cytoskeleton

eLife, 2018
Intermediate filaments (IF) are a major component of the metazoan cytoskeleton and are essential for normal cell morphology, motility, and signal transduction.
Heather J Tarbet, Lee Dolat, Timothy J Smith, Brett M Condon, E Timothy O'Brien III, Raphael H Valdivia, Michael Boyce   +6 more
doaj   +1 more source

Inflammatory Bowel Diseases: Host-Microbial-Environmental Interactions in Dysbiosis [PDF]

Diseases, 2020
Crohn’s Disease (CD) and Ulcerative Colitis (UC) are world-wide health problems in which intestinal dysbiosis or adverse functional changes in the microbiome are causative or exacerbating factors. The reduced abundance and diversity of the microbiome may be a result of a lack of exposure to vital commensal microbes or overexposure to competitive ...
Catherine Colquhoun, Michelle Duncan, George Grant   +2 more
openaire   +3 more sources

Ezrin enhances line tension along transcellular tunnel edges via NMIIa driven actomyosin cable formation

Nature Communications, 2017
Holes in endothelial barriers, called transendothelial cell macroapertures (TEMs), are predicted to be limited by line tension of unknown origin. Here the authors identify an actomyosin cable encircling TEMs and establish a role for ezrin in stabilising ...
Caroline Stefani, David Gonzalez-Rodriguez, Yosuke Senju, Anne Doye, Nadia Efimova, Sébastien Janel, Justine Lipuma, Meng Chen Tsai, Daniel Hamaoui, Madhavi P. Maddugoda, Olivier Cochet-Escartin, Coline Prévost, Frank Lafont, Tatyana Svitkina, Pekka Lappalainen, Patricia Bassereau, Emmanuel Lemichez   +16 more
doaj   +1 more source

Host-Microbial Gut Interactions and Mushroom Nutrition [PDF]

Journal of Food and Nutrition Research, 2018
There is a tremendous complexity of the human gut microbiota in both health and disease states and a healthy microbiota consists of an inter-dependent network of microbes rather than a particular bacterial genera. The microbiota of the gastrointestinal tract is a symbiotic partner of the host as it is crucial for maintaining homeostasis and multiple ...
Victoria Bell, Jorge Ferrão, Eusébio Chaquisse, Tito Fernandes   +3 more
openaire   +1 more source

Dynamic Growth and Shrinkage of the Salmonella-Containing Vacuole Determines the Intracellular Pathogen Niche

Cell Reports, 2019
Summary: Salmonella is a human and animal pathogen that causes gastro-enteric diseases. The key to Salmonella infection is its entry into intestinal epithelial cells, where the bacterium resides within a Salmonella-containing vacuole (SCV).
Virginie Stévenin, Yuen-Yan Chang, Yoann Le Toquin, Magalie Duchateau, Quentin Giai Gianetto, Chak Hon Luk, Audrey Salles, Victoria Sohst, Mariette Matondo, Norbert Reiling, Jost Enninga   +10 more
doaj   +1 more source

Host-microbial interactions in patients with chronic rhinosinusitis [PDF]

Journal of Allergy and Clinical Immunology, 2013
There has been considerable investigation of host-microbial interactions in patients with chronic rhinosinusitis (CRS) in hopes of elucidating mechanisms of disease and better treatment. Most attention has been paid to bacterial infection and potential underlying defects in innate immunity.
openaire   +3 more sources

Microbial Endocrinology: Interaction of the Microbial Hormones with the Host [PDF]

Biomedical Journal of Scientific & Technical Research, 2020
Hip fracture is regarded as the most significant osteoporotic fracture in terms of health consequences, quality of life, and ...
openaire   +1 more source

Candidalysin biology and activation of host cells

mBio
Candida albicans is an opportunistic fungal pathogen that can cause life-threatening systemic infections and distressing mucosal infections. A major breakthrough in understanding C.
Léa Lortal, Claire M. Lyon, Jakob L. Sprague, Johannes Sonnberger, Olivia K. A. Paulin, Don N. Wickramasinghe, Jonathan P. Richardson, Bernhard Hube, Julian R. Naglik   +8 more
doaj   +1 more source

Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor

Nature Communications, 2019
Candida albicans is an opportunistic fungus primarily affecting immunocompromised patients. Here, the authors identify a novel mechanism of host immune stimulation and highlight candidalysin and EGFR signalling components as potential targets for ...
Jemima Ho, Xuexin Yang, Spyridoula-Angeliki Nikou, Nessim Kichik, Andrew Donkin, Nicole O. Ponde, Jonathan P. Richardson, Remi L. Gratacap, Linda S. Archambault, Christian P. Zwirner, Celia Murciano, Rhonda Henley-Smith, Selvam Thavaraj, Christopher J. Tynan, Sarah L. Gaffen, Bernhard Hube, Robert T. Wheeler, David L. Moyes, Julian R. Naglik   +18 more
doaj   +1 more source