Results 41 to 50 of about 195,419 (261)

The presence of Pseudogymnoascus destructans, a fungal pathogen of bats, correlates with changes in microbial metacommunity structure

open access: yesScientific Reports, 2021
Metacommunity theory provides a framework for how community patterns arise from processes across scales, which is relevant for understanding patterns in host-associated microbial assemblages.
Matthew Grisnik   +2 more
doaj   +1 more source

Temporal Transcriptomics of Gut Escherichia coli in Caenorhabditis elegans Models of Aging

open access: yesMicrobiology Spectrum, 2021
Host-bacterial interactions over the course of aging are understudied due to complexities of the human microbiome and challenges of collecting samples that span a lifetime.
Joshua D. Brycki   +9 more
doaj   +1 more source

The role of microbial polysaccharides in host-pathogen interaction [PDF]

open access: yesF1000 Biology Reports, 2009
Bacteria are capable of expressing a diverse range of cell surface polysaccharides from capsules and lipopolysaccharides through teichoic acid molecules to lipoarabinomannans. This review will focus on the expression of capsular polysaccharides and their interaction with the host.
Corbett, D., Roberts, IS.
openaire   +2 more sources

Current Sarcoidosis Models and the Importance of Focusing on the Granuloma

open access: yesFrontiers in Immunology, 2020
The inability to effectively model sarcoidosis in the laboratory or in animals continues to hinder the discovery and translation of new, targeted treatments.
Landon W. Locke   +2 more
doaj   +1 more source

Unveiling viral–host interactions within the ‘microbial dark matter’ [PDF]

open access: yesNature Communications, 2014
Viruses control natural microbial communities. Identification of virus-host pairs relies either on their cultivation or on metagenomics and tentative assignment based on genomic signatures. Both approaches have severe drawbacks when aiming to target such pairs within the uncultured majority. Here we present an unambiguous way to assign viruses to hosts
Martinez-Garcia, Manuel   +4 more
openaire   +4 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

A Modified R-Type Bacteriocin Specifically Targeting Clostridium difficile Prevents Colonization of Mice without Affecting Gut Microbiota Diversity

open access: yesmBio, 2015
Clostridium difficile is a leading cause of nosocomial infections worldwide and has become an urgent public health threat requiring immediate attention. Epidemic lineages of the BI/NAP1/027 strain type have emerged and spread through health care systems ...
Dana Gebhart   +8 more
doaj   +1 more source

Cooperation and Conflict Within the Microbiota and Their Effects On Animal Hosts

open access: yesFrontiers in Ecology and Evolution, 2020
Symbioses between animals and microbes are ubiquitous, and often have drastic fitness effects on both parties. A rapidly growing body of research now shows that many of these effects are driven by social interactions among the symbionts.
Alexandre R. T. Figueiredo   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

MicrobioLink: An Integrated Computational Pipeline to Infer Functional Effects of Microbiome–Host Interactions

open access: yesCells, 2020
Microbiome–host interactions play significant roles in health and in various diseases including autoimmune disorders. Uncovering these inter-kingdom cross-talks propels our understanding of disease pathogenesis and provides useful leads on potential ...
Tahila Andrighetti   +4 more
doaj   +1 more source

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