Results 111 to 120 of about 988,906 (309)

Host Range Restriction and Pathogenicity in the Context of Influenza Pandemic

Emerging Infectious Diseases, 2006
Influenza A viruses cause pandemics at random intervals. Pandemics are caused by viruses that contain a hemagglutinin (HA) surface glycoprotein to which human populations are immunologically naive.
Gabriele Neumann, Yoshihiro Kawaoka
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Risk Assessment Approaches for Ophraella communa as a Biological Control Agent for Ambrosia artemisiifolia in Agricultural Landscapes of Southeastern Central Europe: A Review

Agronomy
Common ragweed, Ambrosia artemisiifolia (Asteraceae), is an invasive weed that causes problems in cropping systems and to human health both in its native range in North and Central America and the introduced range in Europe, Asia, Africa, and Australia ...
Patrice Nduwayo, Urs Schaffner, Sri Ita Tarigan, Zita Dorner, Jozsef Kiss, Nicolas Desneux, Vincent Lesieur, Zoé Rousset, Heinz Müller-Schärer, Stefan Toepfer   +9 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Revenge of the host: Cannibalism, ontogenetic niche shifts, and the evolution of life-history strategies in host-parasitoid systems

, 2012
Question: How does cannibalism in the host alter the evolution of a parasitoid’s oviposition strategy? Can differences in cannibalism risk between parasitized vs. healthy hosts alter the stage foraging of parasitoids?
Rudolf, Volker H.W., Sorrell, Ian, Pedersen, Amy   +2 more
core  

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

The preference–performance relationship as a means of classifying parasitoids according to their specialization degree

Evolutionary Applications, 2019
Host range in parasitoids could be described by the preference–performance hypothesis (PPH) where preference is defined as host acceptance and performance is defined as the sum of all species on which parasitoid offspring can complete their life cycle ...
Lucie S. Monticelli, Le Thu Ha Nguyen, Edwige Amiens‐Desneux, Chen Luo, Anne‐violette Lavoir, Jean‐Luc Gatti, Nicolas Desneux   +6 more
doaj   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Construction and characterization of broad-host-range reporter plasmid suitable for on-line analysis of bacterial host responses related to recombinant protein production

, 2019
Background Bacteria are widely used as hosts for recombinant protein production due to their rapid growth, simple media requirement and ability to produce high yields of correctly folded proteins.
Ertesvåg, Helga, Agnieszka Gawin (6678674), Irla, Marta Katarzyna, Sebastian Hans (6678677), Karl Peebo (1943647), Marta Irla (4571566), Gawin, Agnieszka, Peebo, Karl, Neubauer, Peter, Brautaset, Trygve, Peter Neubauer (1754), Trygve Brautaset (391856), Sebastian, Hans, Helga Ertesvåg (6678680)   +13 more
core   +1 more source