Results 121 to 130 of about 988,906 (309)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Table_9_Novel Self-Transmissible and Broad-Host-Range Plasmids Exogenously Captured From Anaerobic Granules or Cow Manure.XLSX

, 2018
Novel self-transmissible plasmids were exogenously captured from environmental samples by triparental matings with pBBR1MCS-2 as a mobilizable plasmid and Pseudomonas resinovorans as a recipient.
Hideo Dohra (61793), Kengo Inoue (5933036), Moriya Ohkuma (116005), Kosuke Yanagiya (5933030), Kazuhide Kimbara (152138), Masaki Shintani (1386753), Maho Tokuda (5933033), Yoshiaki Maejima (5041988), Hiroki Nakata (342140), Ryota Moriuchi (4454341)   +9 more
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Defining the molecular basis of host range in Papaya ringspot virus (PRSV) Australia

, 2004
The potyvirus Papaya ringspot virus (PRSV) is widespread throughout the world in cucurbits (such as zucchini, watermelon, pumpkin etc) and papaya (papaw).
Jayathilake, Nishantha
core  

Data_Sheet_1_Novel Self-Transmissible and Broad-Host-Range Plasmids Exogenously Captured From Anaerobic Granules or Cow Manure.pdf

, 2018
Novel self-transmissible plasmids were exogenously captured from environmental samples by triparental matings with pBBR1MCS-2 as a mobilizable plasmid and Pseudomonas resinovorans as a recipient.
Hideo Dohra (61793), Kengo Inoue (5933036), Moriya Ohkuma (116005), Kosuke Yanagiya (5933030), Kazuhide Kimbara (152138), Masaki Shintani (1386753), Maho Tokuda (5933033), Yoshiaki Maejima (5041988), Hiroki Nakata (342140), Ryota Moriuchi (4454341)   +9 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

A hypothesis to explain host species differences in resistance to multi-host parasites

Ideas in Ecology and Evolution, 2014
Here, we offer a novel hypothesis to explain why some host species evolve resistance, whereas other related species remain susceptible to a shared parasite species.
Mark R. Forbes, Julia J. Mlynarek
doaj  

Table_8_Novel Self-Transmissible and Broad-Host-Range Plasmids Exogenously Captured From Anaerobic Granules or Cow Manure.XLSX

, 2018
Novel self-transmissible plasmids were exogenously captured from environmental samples by triparental matings with pBBR1MCS-2 as a mobilizable plasmid and Pseudomonas resinovorans as a recipient.
Hideo Dohra (61793), Kengo Inoue (5933036), Moriya Ohkuma (116005), Kosuke Yanagiya (5933030), Kazuhide Kimbara (152138), Masaki Shintani (1386753), Maho Tokuda (5933033), Yoshiaki Maejima (5041988), Hiroki Nakata (342140), Ryota Moriuchi (4454341)   +9 more
core   +1 more source

“Hostbusters”: The Bacterial Endosymbiont Wolbachia of the Parasitoid Wasp Habrobracon hebetor Improves Its Ability to Parasitize Lepidopteran Hosts

Insects
Habrobracon hebetor is a globally acknowledged larval ectoparasitoid that is widely used to control lepidopteran pests. Wolbachia is a natural endosymbiont that regulates various aspects of the insect host biology. The ability of H.
Alsu M. Utkuzova, Ekaterina A. Chertkova, Natalia A. Kryukova, Julia M. Malysh, Yuri S. Tokarev   +4 more
doaj   +1 more source