Results 71 to 80 of about 1,607,402 (303)

Cosmic Evolution of Black Holes and Spheroids. IV. The BH Mass - Spheroid Luminosity Relation [PDF]

, 2009
From high-resolution images of 23 Seyfert-1 galaxies at z=0.36 and z=0.57 obtained with the Near Infrared Camera and Multi-Object Spectrometer on board the Hubble Space Telescope (HST), we determine host-galaxy morphology, nuclear luminosity, total host ...
Auger, Matthew W., Bennert, Vardha Nicola, Blandford, Roger D., Bris, Alexandre Le, Gallagher, Sarah, Malkan, Matthew A., Treu, Tommaso, Woo, Jong-Hak   +7 more
core   +3 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Has HIV evolved to induce immune pathogenesis? [PDF]

, 2008
Human immunodeficiency virus (HIV) induces a chronic generalized activation of the immune system, which plays an important role in the pathogenesis of AIDS.
Bartha, István, Müller, Viktor, Simon, Péter   +2 more
core   +1 more source

Mosquito Host Selection Varies Seasonally with Host Availability and Mosquito Density [PDF]

PLoS Neglected Tropical Diseases, 2011
Host selection by vector mosquitoes is a critical component of virus proliferation, particularly for viruses such as West Nile (WNV) that are transmitted enzootically to a variety of avian hosts, and tangentially to dead-end hosts such as humans. Culex tarsalis is a principal vector of WNV in rural areas of western North America. Based on previous work,
Thiemann, Tara C, Wheeler, Sarah S, Barker, Christopher M, Reisen, William K   +3 more
openaire   +5 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Chemical cues mediating aphid location by natural enemies

European Journal of Entomology, 2008
There is increasing evidence that chemical cues play a pivotal role in host selection by the natural enemies of aphids. We use Vinson's (1976) division of the host selection process into habitat location, host location and host acceptance for both ...
Eduardo HATANO, Grit KUNERT, J.P. MICHAUD, Wolfgang W. WEISSER   +3 more
doaj   +1 more source

Planets spinning up their host stars: a twist on the age-activity relationship

, 2013
It is a long-standing question in exoplanet research if Hot Jupiters can influence the magnetic activity of their host stars. While cool stars usually spin down with age and become inactive, an input of angular momentum through tidal interaction, as seen
Poppenhaeger, K., Wolk, S. J.
core   +1 more source

Development of a selection system for the detection of L-ribose isomerase expressing mutants of Escherichia coli [PDF]

, 2007
L-Arabinose isomerase (E.C. 5.3.1.14) catalyzes the reversible isomerization between L-arabinose and L-ribulose and is highly selective towards L-arabinose.
Beauprez, Joeri, De Maeseneire, Sofie, De Mey, Marjan, De Muynck, Cassandra, Soetaert, Wim, Van Bogaert, Inge, Van der Borght, Jef, Vandamme, Erick   +7 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Host selection through collective decision

ACM Transactions on Autonomous and Adaptive Systems, 2012
In this article, we present a collective decision-making framework inspired by biological swarms and capable of supporting the emergence of a consensus within a population of agents in the absence of environment-mediated communication (stigmergy). Instead, amplification is the result of the variation of a confidence index, stored in individual memory ...
Saffre, F, Simaitis, A
openaire   +2 more sources