Results 41 to 50 of about 2,186,753 (294)

Influence of Host Sialic Acid Receptors Structure on the Host Specificity of Influenza Viruses

Viruses, 2022
Influenza viruses need to use sialic acid receptors to invade host cells, and the α-2,3 and α-2,6 sialic acids glycosidic bonds linking the terminal sialic acids are generally considered to be the most important factors influencing the cross-species ...
Chuankuo Zhao, Juan Pu
doaj   +1 more source

Mortality during dispersal and the cost of host-specificity in parasites: how many aphids find hosts?

, 1998
1. For a full assessment of explanations for the evolution of host-specificity it is necessary to estimate the probability that a dispersing parasite finds a host.
Harrington, R., Ward, S. A., Pickup, J., Leather, S. R.   +3 more
core   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Microphallus pseudopygmaeus (Digenea) infects phylogenetically distant gastropods, with signs of host-linked genetic divergence

Parasite
Host-switching between distantly related host species offers rare insight into how parasites overcome compatibility barriers and initiate evolutionary divergence.
Sokolova Alina I., Galaktionov Kirill V., Gonchar Anna   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Bjerkandera carnegieae comb. nov. ( Phanerochaetaceae , Polyporales ) a wood-decay polypore of cactus

Plant and Fungal Systematics, 2021
Poria carnegieae was described from Arizona growing on the woody ribs of the saguaro cactus, Carnegiea gigantea , and was transferred to Ceriporiopsis due to morphological evidence.
Gerardo Robledo, Karen K. Nakasone, Beatriz Ortiz-Santana   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Trematode Infection Prevalence Increases With Snail Richness: Observations From a 4‐Year Study of Snail–Trematode Interactions

Ecology and Evolution
Digenetic trematodes are valuable study organisms for exploring how biodiversity influences disease. In this study, we investigated the relationship between snail richness and trematode infection prevalence using data from a 4‐year study (2019–2022) of ...
Brooke A. McPhail, Carol M. Frost, Simon J. G. Otto, Patrick C. Hanington   +3 more
doaj   +1 more source

Molecular basis of host specificity in human pathogenic bacteria

Emerging Microbes and Infections, 2014
Pathogenic bacteria display various levels of host specificity or tropism. While many bacteria can infect a wide range of hosts, certain bacteria have strict host selectivity for humans as obligate human pathogens. Understanding the genetic and molecular
Xiaolei Pan, Yang Yang, Jing-Ren Zhang
doaj   +1 more source