Results 111 to 120 of about 434,696 (303)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Community pressure for green behaviour [PDF]

open access: yes, 2012
The desire to avoid rousing community hostility may encourage firms to behave in an environmentally responsible manner. It has been conjectured that such 'informal regulation' could effectively replace formal intervention in some settings, and usefully ...
Heyes, A., Kapur, Sandeep
core  

Sounds of Silence: Organisational trust and decisions to blow the whistle

open access: yesSA Journal of Industrial Psychology, 2008
Whistleblowing is a form of pro-social behaviour that occurs when an employee reports organisational wrongdoing to an authority able to implement corrective action. While a number of social factors may infuence an employee’s decision to blow the whistle,
Elli Binikos
doaj   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

The Impact of Intra-group Interaction on Identity and Action [PDF]

open access: yes, 2013
The unifying theme of the chapters presented in this thesis is that intra-group interaction impacts on in-group identity content, and this content provides a foundation for social action and social behaviour.
Smith, Laura Grace Elizabeth
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Administering Suspect Classes [PDF]

open access: yes, 2017
It has been over forty years since the Supreme Court declared a class suspect under the Equal Protection Clause. In that time, the Court has denied suspect-class status—and the special judicial protections associated with it—to the elderly, the disabled,
Ross, Bertrall L, II
core   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Hubungan Sociability dengan Hostility pada Narapidana Pecandu Shabu (amphetamine) di Lembaga Pemasyarakatan Narkotika Klas IIA Sungguminasa [PDF]

open access: yes, 2017
Pecandu shabu (amphetamine) yang memiliki sociability yang tinggi akan dapat kembali diterima dan bermanfaat di masyarakat. Penelitian ini bertujuan untuk mengetahui hubungan sociability dengan hostility pada narapidana pecandu shabu (amphetamine) di ...
Apriansyah, Andi Muhammad
core  

Seeing red over black and white: popular and media representations of inter-racial relationships as precursors to racial violence [PDF]

open access: yes, 2011
The recent murder in the UK of Anthony Walker attests to the lingering antipathy, indeed hostility, toward intimate inter-racial relationships, especially those involving black men and white women.
Arbery Glenn Cannon   +14 more
core   +1 more source

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