Results 91 to 100 of about 437,508 (301)
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
REPRESENTATION OF PSYCHOLOGICAL PROBLEMS IN KAREN HORNEY’S CHARACTEROLOGICAL ANALYSIS
Вестник Кемеровского государственного университета, 2016 The purpose of research is to establish K. Horney’s views on psychological problems, by means of theoretical analysis of literature. The term "psychological problem" is not mentioned by Karen Horney, however, she describes emotional, cognitive and ...
E. A. Sokolova
doaj +1 more source
Wordsworth's Aeneid and the influence of its eighteenth-century predecessors [PDF]
, 2017 William Wordsworth's attempt at translating Virgil's Aeneid reached as far as Book 4, and mostly survives in manuscript drafts. The literary influences behind it can be illuminated through the poet's correspondence, and analysed more fully by tracing ...
Widmer, Matthias
core +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Social-psychological Aspects of Bullying: Interconnection of Aggressiveness and School Anxiety
Психологическая наука и образование (2007. Online), 2017 Bullying is seen as a variant of aggression. Natural interconnections between contents of teenagers’ fears, anxiety and aggression are analyzed. The longitudinal research results are presented, in the framework of which four consecutive measures of ...
Tarasova S.Ju. +2 more
doaj +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Hosts, Guests and Parasites in Helena Maria Viramontes' “The Cariboo Café”
Miscelánea: A Journal of English and American Studies, 2018 The correlation between immigrants and parasites is a common theme in political discourse. The nation-state assumes the role of a living organism that allows the entrance of an alien, a guest of sorts, who, in turn, endangers the wellbeing of the host ...
Jesús Benito Sánchez
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin +11 more
wiley +1 more source
Sounds of Silence: Organisational trust and decisions to blow the whistle
SA Journal of Industrial Psychology, 2008 Whistleblowing is a form of pro-social behaviour that occurs when an employee reports organisational wrongdoing to an authority able to implement corrective action. While a number of social factors may infuence an employee’s decision to blow the whistle,
Elli Binikos
doaj +1 more source