Results 81 to 90 of about 88,485 (243)

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Subtle cues, major shifts: Eye-tracking insights on how fear and humor legitimize hostility on social media

open access: yesCyberpsychology: Journal of Psychosocial Research on Cyberpspace
Expressions of hostility are widespread online, occurring not only in explicit but even more so in implicit forms. In this study, we trace the subtle yet lasting harmful potential of two prevalent implicit forms of online hostility—fear speech and ...
Ursula Kristin Schmid   +2 more
doaj   +1 more source

Sounds of Silence: Organisational trust and decisions to blow the whistle

open access: yesSA Journal of Industrial Psychology, 2008
Whistleblowing is a form of pro-social behaviour that occurs when an employee reports organisational wrongdoing to an authority able to implement corrective action. While a number of social factors may infuence an employee’s decision to blow the whistle,
Elli Binikos
doaj   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

Relationships between Hostility Guilt and Several Measures of Hostility

open access: yes, 1970
Scores on Mosher's forced-choice Hostility Guilt Scale for females were related to a projective and an objective measure of hostility. The projective measure was the extent to which 70 female undergraduates used the hostile alternative in making up ...
Larry Schneider, Thomas Schill
core   +1 more source

Intrinsic religiosity reduces intergroup hostility under mortality salience [PDF]

open access: yes, 2012
Results of three studies indicate that intrinsic religiosity and mortality salience interact to predict intergroup hostility. Study 1,conducted among 200 American Christians and Jews, reveals that under mortality salience, intrinsic (but not extrinsic or
Abdollahi, Abdolhossein   +4 more
core   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

The relationship between loneliness and aggressiveness in adolescents

open access: yesRussian Journal of Education and Psychology
Background. Adolescence is a critical period of personal development in which the experience of loneliness and aggressive behavior represent interrelated psychological phenomena that threaten social adaptation.
Irina I. Chereminskaya   +2 more
doaj   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

open access: yesFEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa   +4 more
wiley   +1 more source

Religious Affiliation and Manifest Hostility

open access: yes, 1984
To determine the relationship among hostility, guilt, and religion, 167 subjects from introductory psychology courses were given the Buss-Durkee Hostility Inventory and a questionnaire establishing religious affiliation.
Charles R. Geist, Cynthia M. Daheim
core   +1 more source

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