Results 61 to 70 of about 88,485 (243)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Paternal Hostility and Maternal Hostility in European American and African American Families [PDF]

, 2014
The authors examined the hypothesized influence of maternal and paternal hostility on youth delinquency over time. The investigation addressed significant gaps in earlier research on parental hostility, including the neglect of father effects, especially
Ben T. Reeb, Frederick X. Gibbons, Gibbons, Frederick, Conger, Rand, Martin, Monica, Rand D. Conger, Reeb, Ben, Wu, Ed, Ronald L. Simons, Ed Y. Wu, Simons, Ronald, Monica J. Martin   +11 more
core   +1 more source

Psychological factors of social anxiety in students

Консультативная психология и психотерапия, 2011
The study examined psychological factors of social anxiety in students in frames of multi-factor model of emotional disorders by A. Kholmogorova, N. Garanian, described methods and procedures of the research, presented correlations between the level of ...
Pavlova T.S., Kholmogorova A.B.
doaj  

Self‐Managed Housing in Vienna: Managing Ambivalences Between “Invitability” and Resistance

Social Inclusion
This contribution addresses how self‐managed collaborative housing (CoHo) groups engage in and with urban planning in Vienna and thereby how they manage the ambivalence of simultaneously getting involved in established planning and maintaining their ...
Andrea Schikowitz
doaj   +1 more source

“When in Joburg Relatives Show their True Colours”: 'The changing role of the family as a source of social capital among Zimbabwean migrants in Johannesburg'

Nordic Journal of Migration Research, 2015
This study analyses the changing role of the family as a source of social capital in aiding migration, settlement and social integration of Zimbabwean migrants.
Chipo Hungwe
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Aggression and Harm-Avoidant Trait Impede Recovery From Internet Gaming Disorder

Frontiers in Psychiatry, 2018
Background: Relatively little is known about which neuropsychological factors promote recovery from Internet gaming disorder (IGD).Methods: With informed consents, a cohort study was conducted in Seoul metropolitan area, South Korea, to investigate the ...
Seung-Yup Lee, Hae Kook Lee, Soo-young Bang, Hyunsuk Jeong, Hyeon Woo Yim, Yong-Sil Kweon   +5 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Do personality traits such as impulsivity and hostility-aggressiveness predict severity of intent in attempted suicide? Findings from a record based study in South India

Indian Journal of Psychological Medicine, 2015
Background: Little is known about the association of personality traits with intent in attempted suicide. Aims: Our objectives were to assess the levels of selected personality factors among suicide attempters and to examine their association with ...
Vikas Menon, Siddharth Sarkar, Shivanand Kattimani, Kaliaperumal Mathan   +3 more
doaj   +1 more source