Results 41 to 50 of about 43,927 (260)

Effects of asenapine on agitation and hostility in adults with acute manic or mixed episodes associated with bipolar I disorder

open access: yesNeuropsychiatric Disease and Treatment, 2017
Leslie Citrome,1 Ronald Landbloom,2 Cheng-Tao Chang,3 Willie Earley4 1Department of Psychiatry and Behavioral Sciences, New York Medical College, Valhalla, NY, USA; 2Department of Neuroscience, Merck, Whitehouse Station, NJ, USA; 3Biostatistics ...
Citrome L   +3 more
doaj  

Indirect aggression use and its experience in penitentiary incarceration [PDF]

open access: yesProbacja
Introduction: Aim of the research presented in this article is investigation of indirect aggression among inmates. Indirect aggression covers aggressive behaviors toward social position and reputation of the victim, such as ridiculing, disseminating of ...
Krzysztof Nowakowski   +1 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

A STRANGER: PROJECTION OF ALIENATED FEMALE INDIVIDUALITY IN JEAN RHYS’S SHORT STORIES

open access: yesІноземна філологія
The present study examines the prose texts written by Jean Rhys (1890–1979), a British woman writer of modernist literature. It is based on the perusal of several short stories, among others: “In the Rue de l’Arrivée”, “A Night”, “La Grosse Fifi ...
Nadiya Polishchuk
doaj   +1 more source

Adaptation of the Malevolent Creativity Behavior Scale

open access: yesПсихологическая наука и образование, 2019
The paper presents results of adapting the Russian version of the Malevolent Creativity Behavior Scale (MCBS) developed under the guidance of M.Ranko (Hao et al, Front.Psychol.2016.Vol.7.682).The adaptation was carried out in 2016—2018 on a sample of 458
Meshkova N.V.,   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Experience of anger in psychological and works of fathers of the church

open access: yesКонсультативная психология и психотерапия, 2011
This paper discusses the scientific understanding of the experience of anger by psychologists and fathers of the Church. The author demonstrates a fundamental difference between the two approaches, including the purposes of exploring anger.
Gavrilova T.P.
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy