Results 51 to 60 of about 88,485 (243)

An examination of some proposed correlates of depressive illness [PDF]

open access: yes, 1976
Ten depressed subjects, ten recovered subjects and ten control subjects were assessed by the use of the Beck Depression Inventory, the Hostility Direction of Hostility Questionnaire, the Rotter Internal-External Control Scale and the Bene Anthony Family ...
Krenz, Rosemarie Grace Selma
core   +1 more source

Experience of anger in psychological and works of fathers of the church

open access: yesКонсультативная психология и психотерапия, 2011
This paper discusses the scientific understanding of the experience of anger by psychologists and fathers of the Church. The author demonstrates a fundamental difference between the two approaches, including the purposes of exploring anger.
Gavrilova T.P.
doaj  

An offensive realist explanation for the absence of war between Portugal and Spain from 1479 to 1516 [PDF]

open access: yesJournal of Regional Security
For most of the early twenty-first century, the rise of China has raised the question of whether a future war with the US is likely. Less than a decade ago, that question led to a wave of research that incorporated historical case studies back from the ...
Martin González Carlos M.
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Collective Narcissism Moderates the Effect of In-group Image Threat on Intergroup Hostility [PDF]

open access: yes, 2013
Results of four experiments demonstrated that under in-group image threat collective narcissism predicts retaliatory intergroup hostility. Under in-group criticism (vs.
Iskra-Golec, Iskra-Golec   +7 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Malevolent Creativity of Adolescents in Different Socio-political Contexts

open access: yesНациональный психологический журнал
Background. Malevolent creativity is realized in interpersonal interaction in the form of bullying and unethical behavior, harming the psychological health of the victim.
Natalya V. Meshkova   +4 more
doaj   +1 more source

Moralization and the 2012 U.S. Presidential Election Campaign

open access: yesJournal of Social and Political Psychology, 2015
People vary in the extent to which they imbue an attitude with moral conviction; however, little is known about what makes an issue transform from a relatively non-moral preference to a moral conviction. In the context of the 2012 U.S.
Mark J. Brandt   +2 more
doaj   +1 more source

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