Results 111 to 120 of about 5,161,116 (331)

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

EV and PV Capacity Management to Increase Hosting Capacity

, 2023
International audienceAs more electric vehicles (EVs) and photovoltaic (PV) systems are integrated into distribution systems, managing their capacity becomes critical for grid operation and planning.
Alvarez-Hérault, Marie-Cécile
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

FIRST STEPS TOWARDS A STANDARDISED HOSTING CAPACITY METHOD

, 2021
This paper describes the requirements for a standardised hosting capacity method. It outlines the needs and requirements for a standardised methodology as well as ongoing and upcoming standardisation activities in IEEE and IEC.
T. T. de Oliveira, Etherden, Nicholas,, Bollen, Math,, Tavares de Oliveira, Tais,, N. Etherden, M. H. J. Bollen   +5 more
core   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Assessment of Distributed PV Hosting Capacity in Distribution Areas Based on Operating Region Analysis

Algorithms
With the high penetration of distributed photovoltaics (PV) in distribution areas, transformer capacity limits and source–load fluctuations have become key factors constraining PV accommodation.
Xiaofeng Dong, Can Liu, Junting Li, Qiong Zhu, Yuying Wang, Junpeng Zhu   +5 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Photovoltaic hosting capacity assessment in distribution networks

Journal of Electrical Systems and Information Technology
This paper introduces a novel methodology for determining the photovoltaic (PV) hosting capacity of distribution networks by integrating short-circuit impedance analysis with maximum PV penetration assessment under dynamic stability, inverter control ...
Sahar M. Sadek, Amal A. Hassan, Faten H. Fahmy, Amgad A. El-Deib, Hosam K. M. Youssef   +4 more
doaj   +1 more source