Results 91 to 100 of about 5,161,116 (331)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Energies, 2019 There has been an increasing trend of integrating photovoltaic power plants (PVs). One of the important challenges for distribution system operators is to evaluate the total installed power of a PV that a particular network can host (or PV hosting ...
Miha Grabner +4 more
doaj +1 more source
IET Smart Grid, 2022 The capacity of renewable distributed generation (DG) connected in distribution networks is increasing. Use of power electronic interfaces means DG can inject harmonic currents through the point of common coupling into upstream networks.
Wei Sun, Gareth P. Harrison
doaj +1 more source
Performance limits of UK low voltage networks and potential for reactive power compensation [PDF]
, 2013 A deep analyses on real data of five low voltage(LV) networks has been carried out in order to understand the trends of V, I, P, Q and calculated power factor.
Dalla Rizza, Nicola
core
Microbial modification of host long-distance dispersal capacity [PDF]
BMC Biology, 2009 ISSN:1741 ...
Goodacre SL +7 more
openaire +8 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Impact of local flexibility markets on distribution network hosting capacity
The paper investigates the influence of local flexibility markets, modelled with autonomous agents, on the hosting capacity of distribution networks.
Pilo, Fabrizio +4 more
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source