Results 161 to 170 of about 33,160 (253)

Vibronic and Excitonic Structure of a Template-Engineered Molecular-Graphene Heterostructure. [PDF]

open access: yesNano Lett
Kunc J   +8 more
europepmc   +1 more source

Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer

open access: yesAdvanced Science, EarlyView.
Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang   +17 more
wiley   +1 more source

Beyond Biomimetics: Pathology‐Informed Engineering Rescues Reconstituted HDL From Inflammatory Dysfunction for Sepsis Immunotherapy

open access: yesAdvanced Science, EarlyView.
A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou   +12 more
wiley   +1 more source

Spatiotemporally Controlled Sequential Chemo‐Immunotherapy Activates Pyroptosis for Robust Anti‐Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
A glutathione and ultrasound dual‐responsive cerasome achieves sequential co‐delivery of gemcitabine and BMS1166 in tumors. Chemotherapy priming followed by on‐demand PD‐L1 blockade synergistically amplifies anti‐tumor immunity, inhibiting primary tumor growth, distant metastasis and inducing durable immune memory.
Suhui Sun   +9 more
wiley   +1 more source

Ultrafast RIXS of orbital-resolved valence-band reshaping in photoexcited graphite. [PDF]

open access: yesSci Adv
Malvestuto M   +25 more
europepmc   +1 more source

Cross‐scale Material‐Structure Synergy for 2D Metamaterials: Toward Customizable Intelligent Electromagnetic Manipulation in Multiphysics Fields

open access: yesAdvanced Science, EarlyView.
Recent advances in metasurface‐enabled low‐observable technologies are reviewed from the perspective of cross‐scale material–structure synergy. Electromagnetic, thermal, optical, and acoustic stealth are highlighted together with dynamic tuning, programmable coding, data‐driven inverse design, artificial intelligence, multispectral compatibility, and ...
Shuhao Wang   +5 more
wiley   +1 more source

Spatially distributed complex organic matter detected in an ancient river valley in Jezero crater, Mars. [PDF]

open access: yesSci Adv
Murphy AE   +66 more
europepmc   +1 more source

Synergistic Effects in Multistate Black Electro‐Thermochromic Smart Windows for Energy‐Efficient Modulation of Solar Heating

open access: yesAdvanced Science, EarlyView.
Hybrid electro‐thermochromic smart windows are developed for dynamic climate control by integrating a redox‐matched black electrochromic gel with a paraffin‐based thermochromic film. This synergistic combination enables multimodal solar modulation, where photothermal heating from the electrochromic layer triggers thermochromic activation at lower ...
Xilu Wu   +12 more
wiley   +1 more source

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