Modern Management of the Menopause: Are We Measuring What Matters?
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT Objective Assess uptake of the Core Outcomes in Menopause (COMMA) core outcome sets (COS) and examine whether frontline treatments for vasomotor and genitourinary symptoms have been evaluated against these key outcomes. Design Methodological review. Setting Published literature and international clinical trial registries.
Joscelyn Gan +7 more
wiley +1 more source
The influence of habitual physical activity and sedentary behavior on objective and subjective hot flashes at midlife. [PDF]
MenopauseWitkowski S +4 more
europepmc +1 more source
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT Objective To examine the effects of Clinical Pilates (CP) training and aerobic exercise (AE) on menopausal symptoms, depressive symptoms, quality of life (QoL), and sleep quality in postmenopausal women. Design Parallel‐group randomised controlled trial. Setting A Healthy Life Center in Bitlis, Turkey.
Başak Can, Serkan Usgu, Günseli Usgu
wiley +1 more source
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT Background Elinzanetant, a novel, dual neurokinin‐targeted therapy, has been approved in various geographies for the treatment of moderate‐to‐severe vasomotor symptoms (VMS) associated with menopause. Objective To compare the efficacy of elinzanetant with non‐hormonal pharmaceutical treatments (nHT) in alleviating VMS.
Piotr Wojciechowski +8 more
wiley +1 more source
An Evaluation of DNA Methylation Levels and Sleep in Relation to Hot Flashes: A Cross-Sectional Study. [PDF]
J Clin MedOzcivit Erkan IB +7 more
europepmc +1 more source
Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen monotherapy, though historically underutilized, represents a viable alternative in this population. This narrative review
Chloe Thomas +3 more
wiley +1 more source
Differential effects of desvenlafaxine on hot flashes in women with breast cancer taking tamoxifen: a randomized controlled trial. [PDF]
NPJ Breast CancerKim Y +15 more
europepmc +1 more source
Optimizing patrol time in crime hot spots: Replicating the “Koper Curve”
Criminology &Public Policy, EarlyView.Abstract Research Summary In a study published more than 30 years ago, Koper found that patrol visits to crime hot spots were most effective in deterring crime and disorder when they were 11–15 min in length. This finding, popularly known as the “Koper Curve,” has had a substantial influence on police practice and research.
Christopher S. Koper +2 more
wiley +1 more source
Addiction, EarlyView.Abstract Background and aims This study qualitatively explored psychological change processes as described by participants and therapists within a phase 2a clinical trial evaluating the safety, tolerability, and preliminary efficacy of a single dose of intranasal 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT; BPL‐003) administered alongside psychological
Mathieu Seynaeve +6 more
wiley +1 more source
Corrigendum: Glutamatergic and GABAergic neurons in the preoptic area of the hypothalamus play key roles in menopausal hot flashes. [PDF]
Front Aging NeurosciSun Y +10 more
europepmc +1 more source