Results 41 to 50 of about 990,925 (298)

Tracing Hot Spot Motion in Sagittarius A* Using the Next-Generation Event Horizon Telescope (ngEHT)

open access: yesGalaxies, 2023
We propose the tracing of the motion of a shearing hot spot near the Sgr A* source through a dynamical image reconstruction algorithm, StarWarps. Such a hot spot may form as the exhaust of magnetic reconnection in a current sheet near the black hole ...
Razieh Emami   +21 more
doaj   +1 more source

Hot-spot mix in ignition-scale inertial confinement fusion targets

open access: yes, 2013
Mixing of plastic ablator material, doped with Cu and Ge dopants, deep into the hot spot of ignition-scale inertial confinement fusion implosions by hydrodynamic instabilities is diagnosed with x-ray spectroscopy on the National Ignition Facility.
A. J. MacKinnon (19006514)   +41 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Implementation issues with hot spot policing [PDF]

open access: yes, 2023
Although the science behind hot spot policing is robust and grounded in theory, implementation issues prevent it from becoming commonplace in everyday policing. The mounting evidence suggests that “hot spot policing” (Sherman and Weisburd 1995) is rarely

core   +2 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The geno-spatio analysis of Mycobacterium tuberculosis complex in hot and cold spots of Guangxi, China

open access: yesBMC Infectious Diseases, 2020
Background At present, there are few studies on polymorphism of Mycobacterium tuberculosis (Mtb) gene and how it affects the TB epidemic. This study aimed to document the differences of polymorphisms between tuberculosis hot and cold spot areas of ...
Dingwen Lin   +7 more
doaj   +1 more source

Applying machine learning techniques to predict detonation initiation from hot spots

open access: yesEnergy and AI, 2022
As hot spots can be a source of detonation initiation by autoignition in a reactive mixture, understanding hot spot initiated detonation is significantly important for energy-related applications of detonation. Although the Zel’dovich reactivity gradient
Je Ir Ryu
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

An Edge-Guided Deep Learning Solar Panel Hotspot Thermal Image Segmentation Algorithm

open access: yesApplied Sciences, 2023
To overcome the deficiencies in segmenting hot spots from thermal infrared images, such as difficulty extracting the edge features, low accuracy, and a high missed detection rate, an improved Mask R-CNN photovoltaic hot spot thermal image segmentation ...
Fangbin Wang   +5 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

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