Results 61 to 70 of about 39,725 (253)

APIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility

open access: yesBMC Bioinformatics, 2010
Background It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understanding the function of proteins and studying their interactions. Experimental hot
Song Jiangning   +3 more
doaj   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian   +6 more
wiley   +1 more source

Research on Inversion Model of Winding Hot Spot Temperature of 10-kV Oil-Immersed Three-Dimensional Coiled Core Transformer

open access: yesIEEE Access
Realizing online monitoring of the hot spot temperature of grid mounted transformer windings is a challenge for the power industry. The heat exchange process between the internal heat source area and the external field area of the transformer is the ...
Qianyi Chen   +4 more
doaj   +1 more source

A Return to Normality: A Descriptive Qualitative Interview Study Exploring the Patient Experience of Gout Flare Resolution

open access: yesArthritis Care &Research, EarlyView.
Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart   +5 more
wiley   +1 more source

SERS Immunosensor of Array Units Surrounded by Particles: A Platform for Auxiliary Diagnosis of Hepatocellular Carcinoma

open access: yesNanomaterials, 2020
Hepatocellular carcinoma (HCC) is one of the diseases with high mortality worldwide, so its early diagnosis and treatment have attracted much attention.
Mingyu Cheng   +6 more
doaj   +1 more source

Thermomechanical Fatigue and Creep–Fatigue Interaction of Inconel 718 Additively Manufactured by Laser Beam Powder Bed Fusion

open access: yesAdvanced Engineering Materials, EarlyView.
Thermomechanical fatigue tests of laser beam powder bed fusion (PBF‐LB) Inconel 718 show that the additively manufactured material reaches almost the lifetimes of conventionally‐rolled material under no‐dwell conditions. Introducing dwell times at the maximum temperature markedly reduces the lifetimes due to pronounced grain boundary sliding associated
Stefan Guth   +6 more
wiley   +1 more source

FPGA implementation of hot spot detection in infrared video [PDF]

open access: yesIET Irish Signals and Systems Conference (ISSC 2010), 2010
This paper describes a Hardware Description Language (HDL) based fully customizable module for real-time Infrared (IR) hot spot detection and feature extraction from a video stream. The aim of the research was to investigate and evaluate possible solutions for object detection using connected component labelling that could be implemented within a ...
R. Walczyk, A. Armitage, T.D. Binnie
openaire   +1 more source

Pyramidal Structures on Yttria‐Stabilized Zirconia after High Temperature Exposure at 1500°C: New Features on an Old Material

open access: yesAdvanced Engineering Materials, EarlyView.
New features on yttria‐stabilized zirconia after exposure at 1500°C: Newly discovered pyramidal structures on an old material. After exposure at 1550°C on the cross section of YSZ new features, namely pyramidal structures are discovered. These structures grow with time, increase in numbers, appear as singularities, are often arranged in strings, and ...
Doris Sebold   +2 more
wiley   +1 more source

Solid‐State Diffusion and Intermetallic Phase Formation in Roll‐Bonded Mg–Zn Composites With Kirigami‐Patterned Inlay

open access: yesAdvanced Engineering Materials, EarlyView.
Mg–Zn composites with a thickness of 0.21 mm were fabricated using roll bonding of a kirigami‐patterned Mg alloy inlay within a Zn matrix. Thermal activation following this process led to the formation of tailored intermetallic structures, which provided the composite with enhanced flexural strength.
Yaroslav Frolov   +4 more
wiley   +1 more source

Understanding the Stochastic Nature of Process Parameter Development of Blown Powder Laser Beam Directed Energy Deposition Additive Manufacturing of Pure Molybdenum

open access: yesAdvanced Engineering Materials, EarlyView.
Identified through the use of statistical design of experiments and metallographic investigation, this study exposes the stochastic origins of intergranular cracks in blown powder laser beam directed energy deposition additive manufacturing of pure molybdenum. It further demonstrates a successful crack mitigation approach with direct correlation to the
Nathaniel J. Lies   +2 more
wiley   +1 more source

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