Results 31 to 40 of about 56,492 (254)

Site-based data curation based on hot spring geobiology. [PDF]

PLoS ONE, 2017
Site-Based Data Curation (SBDC) is an approach to managing research data that prioritizes sharing and reuse of data collected at scientifically significant sites.
Carole L Palmer, Andrea K Thomer, Karen S Baker, Karen M Wickett, Christie L Hendrix, Ann Rodman, Stacey Sigler, Bruce W Fouke   +7 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Phylogeographical and population genetics of Polyspora sweet in China provides insights into its phylogenetic evolution and subtropical dispersal

BMC Plant Biology
Background Geological movements and climatic fluctuations stand as pivotal catalysts driving speciation and phylogenetic evolution. The genus Polyspora Sweet (Theaceae), prominently found across the Malay Archipelagos and Indochina Peninsula in tropical ...
Zhifeng Fan, Can Gao, Lifang Lin
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Precipitation-driven hydrological characteristics of Bei hot spring: Insights from dynamic variations of natural tracers (water discharge, water temperature, and electrical conductivity)

Journal of Hydrology: Regional Studies
Study region: Bei hot spring in Chongqing, China. Study focus: The primary objectives of this research are to analyze geothermal water characteristics of Bei hot spring, simulate the dynamic process of water discharge (Q), groundwater temperature (Tw ...
Yongli Guo, Fuxiang Chi, Qiong Xiao, Matej Blatnik   +3 more
doaj   +1 more source

Genomic adaptations enabling Acidithiobacillus distribution across wide-ranging hot spring temperatures and pHs

Microbiome, 2021
Background Terrestrial hot spring settings span a broad spectrum of physicochemistries. Physicochemical parameters, such as pH and temperature, are key factors influencing differences in microbial composition across diverse geothermal areas. Nonetheless,
Chanenath Sriaporn, Kathleen A. Campbell, Martin J. Van Kranendonk, Kim M. Handley   +3 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

It Was Hot Springs. [PDF]

JAMA: The Journal of the American Medical Association, 1895
Tennessee State Board of Health, Nashville, Dec. 20,1895. To the Editor: —On page 1000, December 7,Journal of the American Medical Association, second column, line 10 (from bottom), " Little Rock" should read "Hot Springs." Much fault is found with me because of this error.
openaire   +1 more source

What Makes A Hot Spring, Hot?

Warta Geologi, 2022
Hot springs naturally are groundwater that emerges to the surface after being heated up by geothermal activities. There are various classifications of hot springs according to the surface temperature. Still, in Malaysia, it is referred to as the spring that is higher than an average body temperature or 40 °C and above.
Nurul Afiqah Rosli, Mohammad Noor Akmal Anuar, Muhammad Hasiib Mansor, Nur Syazwani Izzati Abdul Rahim, Mohd Hariri Arifin   +4 more
openaire   +1 more source