Results 41 to 50 of about 931,743 (352)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Genomic adaptations enabling Acidithiobacillus distribution across wide-ranging hot spring temperatures and pHs

open access: yesMicrobiome, 2021
Background Terrestrial hot spring settings span a broad spectrum of physicochemistries. Physicochemical parameters, such as pH and temperature, are key factors influencing differences in microbial composition across diverse geothermal areas. Nonetheless,
Chanenath Sriaporn   +3 more
doaj   +1 more source

ANALISIS KEPUASAN WISATAWAN TERHADAP PRODUK WISATA DI MARIBAYA NATURAL HOT SPRING RESORT LEMBANG KABUPATEN BANDUNG BARAT [PDF]

open access: yes, 2016
Taman Wisata Maribaya dikelola oleh Pemerintah Daerah yang bekerjasama dengan PT. Akurasi Kuat Mega Indonesia. Kemudian pengelola merenovasi dan mengubah konsep, baik dari segi penampilan maupun pelayanan dan diubah namanya menjadi Maribaya Natural Hot ...
Ardiansyah, Yudi
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Precipitation-driven hydrological characteristics of Bei hot spring: Insights from dynamic variations of natural tracers (water discharge, water temperature, and electrical conductivity)

open access: yesJournal of Hydrology: Regional Studies
Study region: Bei hot spring in Chongqing, China. Study focus: The primary objectives of this research are to analyze geothermal water characteristics of Bei hot spring, simulate the dynamic process of water discharge (Q), groundwater temperature (Tw ...
Yongli Guo   +3 more
doaj   +1 more source

Microbial diversity in the thermal springs within Hot Springs National Park [PDF]

open access: yes, 2018
The thermal water systems of Hot Springs National Park (HSNP) in Hot Springs, Arkansas exist in relative isolation from other North American thermal systems. The HSNP waters could therefore serve as a unique center of thermophilic microbial biodiversity.
Moran, Matthew D   +2 more
core   +3 more sources

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

It Was Hot Springs. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1895
Tennessee State Board of Health, Nashville, Dec. 20,1895. To the Editor: —On page 1000, December 7,Journal of the American Medical Association, second column, line 10 (from bottom), " Little Rock" should read "Hot Springs." Much fault is found with me because of this error.
openaire   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

What Makes A Hot Spring, Hot?

open access: yesWarta Geologi, 2022
Hot springs naturally are groundwater that emerges to the surface after being heated up by geothermal activities. There are various classifications of hot springs according to the surface temperature. Still, in Malaysia, it is referred to as the spring that is higher than an average body temperature or 40 °C and above.
Nurul Afiqah Rosli   +4 more
openaire   +1 more source

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