Results 31 to 40 of about 3,349,877 (335)
The Formation and Evolution of Shear Bands in Plane Strain Compressed Nickel-Base Superalloy
Metals, 2018 The formation and evolution of shear bands in Inconel 718 nickel-base superalloy under plane strain compression was investigated in the present work.
Bin Tang +5 more
doaj +1 more source
Journal of Materials Research and Technology, 2021 Hot deformation characteristics of a 25Cr–6Mn–3Ni–1Mo–3W lean duplex stainless steel containing high C and N contents were elucidated. Hot compression tests were performed at temperatures of 600–1100 °C and strain rates of 0.01–10 s−1.
Joonoh Moon +5 more
doaj +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Hot working behavior of hot-extruded Ni-Co-Cr-based powder metallurgy superalloy
Cailiao gongcheng, 2020 Isothermal compression tests were carried out on a Gleeble-3500D thermal simulation machine. The hot compression deformation behavior of a new hot-extruded Ni-Co-Cr-based powder metallurgy(P/M) superalloy at the temperatures from 1020℃ to 1110℃ with the ...
LI Hui-zhong +5 more
doaj +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
FEBS Open Bio, EarlyView.Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
A Modular multilevel converter with hybrid redundant strategy for HVDC system
Energy Reports, 2021 As a typical voltage source converter topology, Modular multilevel converter (MMC) widespread used in high voltage direct current (MMC-HVDC) power systems due to its modularization, low harmonic, easy expansion, and high efficiency.
Wanli Jing +5 more
doaj +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Corrosion resistance mechanism of postmortem corundum-mullite refractories used in hot stoves
Journal of Asian Ceramic Societies, 2022 Alkali attack of aluminosilicate refractories has been a long-term problem in the industry. In this paper, XRD, SEM, and CT scanning methods were used to analyze the phase and structure characteristics of postmortem corundum-mullite refractory used in ...
Xiu-Hua Zhang +5 more
doaj +1 more source