Results 51 to 60 of about 4,479,146 (391)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

An Incremental Physically-Based Model of P91 Steel Flow Behaviour for the Numerical Analysis of Hot-Working Processes

, 2018
This paper is aimed at modelling the flow behaviour of P91 steel at high temperature and a wide range of strain rates for constant and also variable strain-rate deformation conditions, such as those in real hot-working processes.
A. Murillo-Marrodán, E. S. Puchi-Cabrera, E. García, M. Dubar, F. Cortés, L. Dubar   +5 more
semanticscholar   +1 more source

Deterministic 1-k routing on meshes with applications to worm-hole routing [PDF]

, 1993
In $1$-$k$ routing each of the $n^2$ processing units of an $n \times n$ mesh connected computer initially holds $1$ packet which must be routed such that any processor is the destination of at most $k$ packets. This problem reflects practical desire for
Kaufmann, M., Sibeyn, J.
core  

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Energy and Exergy Analyses of a Novel Combined Heat and Power System Operated by a Recuperative Organic Rankine Cycle Integrated with a Water Heating System

Energies, 2022
This study reports the thermodynamic analysis of a high-temperature recuperative organic Rankine cycle comprising a water heating system that can provide a net power of 585.7 kW and hot water for domestic use at 35 °C.
Babras Khan, Man-Hoe Kim
doaj   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

VHMPID: a new detector for the ALICE experiment at LHC

, 2011
This article presents the basic idea of VHMPID, an upgrade detector for the ALICE experiment at LHC, CERN. The main goal of this detector is to extend the particle identification capabilities of ALICE to give more insight into the evolution of the hot ...
Agócs, A. G., Alfaro, R., Barnaföldi, G. G., Bellwied, R., Bencze, Gy., Berényi, D., Boldizsár, L., Cuautle, E., De Cataldo, G., Di Bari, D., Di Mauro, A., Dominguez, I., Futó, E., García, E., Hamar, G., Harris, J., Harton, A., Kovács, L., Lipusz, Cs., Lévai, P., Markert, C., Martinengo, P., Martinez, M. I., Mastromarco, M., Mayani, D., Molnár, L., Nappi, E., Ortiz, A., Paić, G., Pastore, C., Patino, M. E., Perini, D., Perrino, D., Peskov, V., Pinsky, L., Piuz, F., Pochybová, S., Smirnov, N., Song, J., Timmins, A., Varga, D., Vargas, A., Vergara, S., Volpe, G., Yi, J., Yoo, I. -K.   +45 more
core   +2 more sources

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Liver‐specific lncRNAs associated with liver cancers

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina, Roman K. Makarchenko, Maria P. Rubtsova, Olga A. Dontsova   +3 more
wiley   +1 more source

Plastic behavior of medium carbon vanadium microalloyed steel at temperatures near g « a transformation

Materials Research, 2001
Dilatometric techniques were used to build the continuous cooling transformation (CCT) diagram for a medium carbon microalloyed steel; the microstructure and hardness were determined at different cooling rates. The mechanical behavior of the steel in the
Lourenço N.J., Jorge Jr. A.M., Rollo J.M.A., Balancin O.   +3 more
doaj