Results 131 to 140 of about 335,663 (313)

Advances in MoS2‐Au Nanostructured Platforms for Cancer‐Derived miRNA Detection

open access: yesAdvanced Materials Interfaces, EarlyView.
This figure presents the roadmap and scope of this review on microRNA detection technologies, with emphasis on MoS2 and MoS2–Au hybrid nanostructures. It traces the evolution from conventional assays to MoS2‐based SERS platforms, highlights synthesis, interfacial chemistry, and signal‐enhancement mechanisms, and summarizes key challenges and future ...
Faith Mokobi Zablon   +2 more
wiley   +1 more source

Transducers Across Scales and Frequencies: A System‐Level Framework for Multiphysics Integration and Co‐Design

open access: yesAdvanced Materials Technologies, EarlyView.
Transducers convert physical signals into electrical and optical representations, yet each mechanism is bounded by intrinsic trade‐offs across bandwidth, sensitivity, speed, and energy. This review maps transduction mechanisms across physical scale and frequency, showing how heterogeneous integration and multiphysics co‐design transform isolated ...
Aolei Xu   +8 more
wiley   +1 more source

The landscape of research on ferroptosis under hypoxic conditions: a bibliometric analysis

open access: yesFrontiers in Pharmacology
BackgroundFerroptosis is a newly identified type of iron-dependent cell death that characterized by an increase in intracellular iron ions, which disrupt the balance of the cellular lipid peroxidation system, causing lipid peroxidation and ultimately ...
Di Yu   +4 more
doaj   +1 more source

Degradation Mechanisms in PEM Water Electrolysis: Diagnosis and Impact

open access: yesAdvanced Materials Technologies, EarlyView.
This review provides an analysis of degradation mechanisms in proton electrolyte membrane water electrolyzers (PEMWE), focusing on all key components. It discusses diagnostic and measurement techniques for evaluating degradation, less‐studied mechanisms, and an expert survey.
Annik Bernhardt   +11 more
wiley   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

open access: yesAdvanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin   +11 more
wiley   +1 more source

Indole‐3‐Propionic Acid Improves Alveolar Development Impairment via Targeting VAMP8‐mediated SNAREs Complex Formation in Bronchopulmonary Dysplasia

open access: yesAdvanced Science, EarlyView.
This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang   +14 more
wiley   +1 more source

Highly Resolved Community Sewage Metagenomics Unveiling Landscape and Transmission Patterns of Antibiotic Resistome in Hong Kong Populations

open access: yesAdvanced Science, EarlyView.
A large‐scale, high‐resolution antimicrobial resistance (AMR) surveillance in Hong Kong community sewage combining short‐ and long‐read sequencing. The resistome profile is comprehensively characterized, and this upstream sampling strategy demonstrated superiority in reflecting the human gut resistome.
Jiahui Ding   +11 more
wiley   +1 more source

Global research hotspots and trends of acupuncture regulating neuroplasticity: a bibliometric analysis from 2005 to 2024

open access: yesFrontiers in Neurology
BackgroundAcupuncture has been widely used to relieve or cure various diseases. In this study, bibliometrics was used to comprehensively analyze the research focus and development trend of acupuncture regulating neuroplasticity, to provide new insights ...
Qiaoli Zhang   +5 more
doaj   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

open access: yesAdvanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun   +23 more
wiley   +1 more source

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