Results 151 to 160 of about 267,219 (299)

Curvature‐Controlled Field Effect Enables Thermal Localization for Low‐Temperature C─F Bond Activation

Advanced Science, EarlyView.
High‐curvature γ‐Al2O3 nanoneedles concentrate heat into nanoscale hotspots under identical external heating, amplifying local temperature and accelerating CF4 decomposition. By linking curvature‐induced thermal localization to lower apparent activation barriers and enhanced intermediate formation, this work reveals geometry as a powerful design ...
Hang Zhang, Jialin Zheng, Xiaojian Wang, Hao Yu, Diya Xie, Wenjie Luo, Minghui Yang, Kang Liu, Yuxia Duan, Zhang Lin, Liyuan Chai, Emiliano Cortés, Min Liu   +12 more
wiley   +1 more source

Mutational landscape and molecular bases of echinocandin resistance in Saccharomyces cerevisiae. [PDF]

Genetics
Durand R, Torbey AG, Giguere M, Pageau A, Dubé AK, Lagüe P, Landry CR.   +6 more
europepmc   +1 more source

PDGFRα+/Integrin α2+ Fibroblasts Orchestrate Tumor Budding in Oral Squamous Cell Carcinoma via Mechano‐Metabolic Symbiosis: E‐Cadherin/Integrin α2β1 Adhesion and Mitochondrial Transfer

Advanced Science, EarlyView.
PDGFA/PDGFRα signaling recruits CAFs to OSCC nests, and CAF‐OSCC contact drives tumor budding invasion. Mechanistically, heterotypic adhesion via E‐cadherin/integrin α2β1 activates YAP signaling in OSCC cells, inducing EMT. Concurrently, CAFs transfer mitochondria through TNTs, supplying ATP to fuel invasion.
Yufang Liu, Jiao Li, Juan Liu, Qi Dong, Haoyang Zhang, Yanjin Wang, Huibing Li, Ye Guan, Lei Cao, Manqing Zhang, Fangning Guo, Xue Liu, Zhen Yang, Mengmeng Lu, Hui Liu, Laiping Zhong, Tong Ji, Tingjiao Liu   +17 more
wiley   +1 more source

Ki-67 Quantification in Breast Cancer: A Comparison of Hotspot and Global Scoring Methods Using a Standardized Android Application. [PDF]

Cureus
Patel M, Jawalkar S.
europepmc   +1 more source

Multi‐tissue Metabolic GWAS and Drought‐Responsive Multi‐omics Reveal the Genetic Basis of the Quinoa Metabolome

Advanced Science, EarlyView.
A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker, Elodie L. Rey, Clara Stanschewski, Regina Wendenburg, Annabella Klemmer, Markéta Macho, Venkatesh P. Thirumalaikumar, Noha O. Saber, Aleksandra Skirycz, Alisdair R. Fernie, Mark Tester, Saleh Alseekh   +11 more
wiley   +1 more source

Optogenetic Hedonic Hotspots in the Orbitofrontal Cortex and Insula: Causing Enhancement of Sweetness "Liking". [PDF]

J Neurosci
Morales I, Berridge KC.
europepmc   +1 more source

An Efficient Detection Platform Based on Mesoporous Au@Cr2O3 Particles with Schwarz P Surface for Precise Periodontitis Metabolite Profiling

Advanced Science, EarlyView.
A non‐invasive periodontitis diagnosis platform was developed using Au nanoparticles‐decorated mesoporous Cr2O3 (Au@mCr2O3) particles with Schwarz P surface as matrix for saliva metabolic fingerprinting (SMFs) analysis via MALDI‐MS. With the assistance of machine learning of SMFs, this platform enables efficient diagnosis and the screening of potential
Yue Sun, Yan Wang, Fangying Shi, Wenhe Xie, Yiding Zhang, Heyuhan Zhang, Chunhui Deng, Limin Wu, Meihua Chen, Yonghui Deng   +9 more
wiley   +1 more source

Panel-negative strategy for suspected fusion-driven papillary thyroid carcinoma. [PDF]

Thyroid Res
Okubo Y, Takada I, Kadoya M, Toda S, Wada S, Masudo K, Miyagi Y, Hayashi H.   +7 more
europepmc   +1 more source

Chiral Plasmonic Printing of Discrete Hierarchical Chiral Au@Chiral Ag Semi‐Core‐Shell Nanorods With Chiral Plasmon‐Enhanced Photocatalysis

Advanced Science, EarlyView.
Chiral plasmonic printing uses CPL as a chiral stimulus to guide asymmetric Ag deposition on chiral Au NRs seeds. Under CPL, hot carriers reduce Ag+, and the process is controlled by both the CPL handedness and the chiral SPR. L‐dc Au generates more hot electrons under LCP than RCP, while D‐dc Au shows the opposite, revealing chiral photon‐selective ...
Yaxin Cao, Haoyu Li, Mengli Wu, Shengshi Fan, Shenli Wang, Haibo Zhou, Guangchao Zheng   +6 more
wiley   +1 more source

Novel insights into the histopathological characteristics of immune checkpoint inhibitor-related myocarditis. [PDF]

ESC Heart Fail
Nishikawa T, Otani T, Yamamoto H, Yasui T, Shingu M, Osumi Y, Ishibashi K, Ikeda Y, Nonaka A, Fukuda Y, Murai R, Furukawa Y, Hara S, Sawaki D, Hiranuma N, Ohashi Y, Takaya T, Asada Y, Ishii N, Kubo T, Kinugasa Y, Date E, Iizuka N, Sakamoto N, Kitai T, Izumi C, Amemiya K, Ohta-Ogo K, Nishihira K, Kinugasa M, Shimokawa T, Tamita K, Fujita M, Hatakeyama K.   +33 more
europepmc   +1 more source