Tumor‐Infiltrating mregDCs Restrain Anti‐Tumor Immunity in Early Relapse HCC
Tumor‐infiltrating mregDCs are regulated by the TNFR2‐non‐canonical NF‐κB axis, which is mediated by TNF‐α secreted by CD161+CD8+ T cells. These mregDCs recruit CD161+CD8+ T cells via the CCL20‐CCR6 axis, forming a positive feedback loop that enhances immunosuppression, promotes early recurrence of HCC, and further confirms TNFR2 as a key therapeutic ...
Zefan Zhang +13 more
wiley +1 more source
Novel insights into the histopathological characteristics of immune checkpoint inhibitor-related myocarditis. [PDF]
Nishikawa T +33 more
europepmc +1 more source
Bilateral SERS‐Microneedle Patch for Co‐Diagnosis of Diabetes Mellitus and Tuberculosis Comorbidity
Our study introduced a U@mP@Au‐mediated bilateral SERS‐microneedle patch for analyzing glucose levels from ISF and sensitively detecting TB biomarkers from sputum, respectively. This integrated dual‐analyte detecting platform can be used for co‐diagnosis of diabetes mellitus (DM) and tuberculosis (TB) comorbidity, which was demonstrated in ex vivo ...
Xueqin Huang +12 more
wiley +1 more source
Geometry‐Controlled Assembly of Self‐Standing Nanorods With Undisturbed Plasmonics
This study reports a geometry‐driven assembly strategy to vertically align Au@Ag core–shell nanorods on PS beads. This well‐defined architecture enables the preservation of the intrinsic optical response of individual nanorods. Thus, demonstrate a highly reproducible SERS enhancement with exceptional uniformity.
Yoel Negrin‐Montecelo +5 more
wiley +1 more source
Clinicopathological characterization of cervical squamous cell carcinoma with <i>PIK3CA</i> hotspot mutation: A single-institution study. [PDF]
Murray J +8 more
europepmc +1 more source
Quantum Photothermal Self‐Monitoring Fiber Probes for In Vivo Photothermal Therapy
A miniaturized quantum photothermal fiber probe based on a metal/polymer/glass composite optoelectronic fiber that simultaneously guides lightwave and microwave was developed for the first time. The probe achieves enhanced photothermal conversion (13°C/mW, 25°C–120°C range) while providing real‐time self‐monitoring with 0.2°C thermal resolution at the ...
Wanjun Li +12 more
wiley +1 more source
Defining hotspot for estimation of Ki-67 proliferation index of neuroendocrine tumors: QuPath algorithm vs. manual assessment. [PDF]
Oganesyan R +9 more
europepmc +1 more source
Neuromorphic Near‐Sensor and In‐Sensor Computing Enabled by Next‐Generation Material‐Based Sensors
This Review presents a structural framework that classifies neuromorphic sensing into near‐sensor and in‐sensor architectures, clarifying physical coupling between sensing and computation. The framework connects neural and synaptic device functions with recent advances in optical, mechanical, and chemical sensing, compares energy consumption and ...
Su Yeon Jung +7 more
wiley +1 more source
Correction for McDonald et al., Can auxiliary indicators improve COVID-19 forecasting and hotspot prediction? [PDF]
europepmc +1 more source

