Results 41 to 50 of about 335,663 (313)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Epidemiological features and spatial-temporal clustering of visceral leishmaniasis in mainland China from 2019 to 2021

open access: yesFrontiers in Microbiology, 2022
BackgroundVisceral leishmaniasis (VL) is a serious vector-borne disease in central and western China. In recent years, the number of VL cases increased gradually, particularly the mountain-type zoonotic visceral leishmaniasis (MT-ZVL).
Yuanyuan Li   +9 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Experimenting with a Battery-Based Mitigation Technique for Coping with Predictable Partial Shading

open access: yesEnergies, 2022
In this paper, the authors propose to use batteries to improve the performance of grid-connected photovoltaic plants when their photovoltaic fields are subject to partial shading phenomena.
Rosario Carbone, Cosimo Borrello
doaj   +1 more source

Imaging of Thermal Domains in ultrathin NbN films for Hot Electron Bolometers

open access: yes, 2007
We present low-temperature scanning electron microscopy (LTSEM) investigations of superconducting microbridges made from ultrathin NbN films as used for hot electron bolometers.
Doenitz, D.   +4 more
core   +1 more source

Chandra Observations of 3C Radio Sources with z<0.3: Nuclei, Diffuse Emission, Jets and Hotspots [PDF]

open access: yes, 2010
We report on our Chandra Cycle 9 program to observe half of the 60 (unobserved by Chandra) 3C radio sources at ...
A. Capetti   +46 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Steady-State Simulation of a Fixed-Bed Reactor for the Total Oxidation of Volatile Organic Components: Application of the Barkelew Criterion

open access: yesChemEngineering
A steady-state tubular reactor for total oxidation reaction under typical industrial conditions in the removal of volatile organic components (VOC) is described using a one-dimensional heterogeneous reactor model with intraparticle diffusion, using a ...
Philippe M. Heynderickx   +1 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Three new species of Niphargidae family added to the list of subterranean amphipods (Crustacea: Amphipoda) in Slovenia

open access: yesNatura Sloveniae
Since the last comprehensive checklist of amphipods in 2021, three new species of subterranean amphipods have been confirmed for Slovenia: Niphargus danielopoli, N. lurensis and N. julius.
Cene Fišer, Teo Delić, Maja Zagmajster
doaj   +1 more source

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