Results 121 to 130 of about 85,194 (289)

An Ultra‐Wideband Metasurface Perfect Absorber Based on Hybrid Absorption Modes

open access: yesAdvanced Photonics Research, EarlyView.
A Ge2Sb2Te5 metasurface absorber enables polarization‐independent, ultrabroadband (UV–NIR) light absorption with high angular tolerance. Its performance stems from overlapping electric and magnetic dipole resonances in a symmetric structure, achieving 94% average absorption and maintaining 83% even at 70° incidence, promising for integrated ...
Dingbang Liu   +8 more
wiley   +1 more source

Enhanced Trapping with an Optimized Graphene‐Based Bowtie Plasmonic Nanotweezer: Design, Analysis, and Bioanalytical Applications

open access: yesAdvanced Photonics Research, EarlyView.
A graphene‐based bowtie plasmonic nanotweezer is designed and optimized using particle swarm optimization and transfer matrix analysis. The structure achieves strong field confinement, delivering trapping forces up to 6 nN W−1 for 10 nm bioparticles with sixfold lower power requirements than conventional designs.
Saba Ebrahimpanah   +2 more
wiley   +1 more source

Indole‐3‐Propionic Acid Improves Alveolar Development Impairment via Targeting VAMP8‐mediated SNAREs Complex Formation in Bronchopulmonary Dysplasia

open access: yesAdvanced Science, EarlyView.
This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang   +14 more
wiley   +1 more source

Prevalence and Risk Mapping of Intestinal Parasites in the “Hungry Valleys” Region of Slovakia

open access: yesPathogens
Helminthiases remain a significant global health concern, affecting both the Global South and increasingly the Global North. In Slovakia, intestinal parasitic infections impact marginalised populations, particularly the population of Roma inhabitants ...
Lukáš Ihnacik   +3 more
doaj   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

open access: yesAdvanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun   +23 more
wiley   +1 more source

Spatiotemporal evolution of dengue hotspots in Kuantan, Malaysia: A decade-long geospatial analysis for adaptive vector control

open access: yesClinical Epidemiology and Global Health
Problem considered: Dengue continues to pose a major public health burden in Malaysia, particularly in rapidly urbanising districts where shifting land-use patterns influence transmission dynamics.
Zulkifli Abdul Hadi   +3 more
doaj   +1 more source

Unveiling Global Diversity of Patescibacteriota and Functional Interactions with Host Microbes

open access: yesAdvanced Science, EarlyView.
Patescibacteriota represents a diverse group of ultra‐small epibiotic bacteria, which is largely overlooked. By integrating ribosomal protein S3‐based community profiling with MAG‐based metabolic potential analyses, this study provides new insights into their distribution, diversity, and potential interactions with other bacteria across diverse ...
Yanhan Ji   +12 more
wiley   +1 more source

The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation

open access: yesAdvanced Science, EarlyView.
ASXL1's long IDR encodes an electrostatic “basic platform + acidic brake” that autoregulates condensation. Truncation at a clinical hotspot lifts this brake, forming condensates that retarget BRD2, remodel local chromatin accessibility, and impair neutrophil maturation.
Xiao Fang, Qiwei Li, Wenqing Zhang
wiley   +1 more source

Latitudinal Asymmetry in the Dayside Atmosphere of WASP-43b

open access: yesThe Astrophysical Journal Letters
We present two-dimensional near-infrared temperature maps of the canonical hot Jupiter WASP-43b using a phase-curve observation with JWST NIRSpec/G395H. From the white-light planetary transit, we improve constraints on the planet’s orbital parameters and
Ryan C. Challener   +11 more
doaj   +1 more source

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