Results 21 to 30 of about 117,481 (252)

Current hotspots and trends in cancer metabolic reprogramming: a scientometric analysis

Frontiers in Immunology
BackgroundMetabolic reprogramming (MR) in cancer (CA) has been a focus of intense research in the recent two decades. This phenomenon has attracted great interest because it offers potential targets for cancer therapy.
Shanshan Yang, Miaomiao Lin, Shaodong Hao, Hui Ye, Xuezhi Zhang   +4 more
doaj   +1 more source

Research Hot Spots and Trends on Melatonin From 2000 to 2019

Frontiers in Endocrinology, 2021
Research on melatonin remains one of the major hot spots in the field of disease treatment, but relevant data are numerous. The purpose of this study was to quantitatively and qualitatively analyze the progress of melatonin research through the method of
Yan Meng, Zhengbo Tao, Siming Zhou, Wacili Da, Lin Tao   +4 more
doaj   +1 more source

Numerical Investigation of Interventions to Mitigate Heat Stress: A Case Study in Dubai

Energies
Urbanization and changes in microclimate have negative impacts on outdoor thermal comfort, making urban design more important. This study aims to improve outdoor thermal comfort in a local climate zone (LCZ) in Dubai using computational fluid dynamics ...
Talha Batuhan Korkut, Ahmed Rachid
doaj   +1 more source

The Socio-Economic and Environmental Variables Associated with Hotspots of Infrastructure Expansion in South America

Remote Sensing, 2020
The built environment, defined as all human-made infrastructure, is increasing to fulfill the demand for human settlements, productive systems, mining, and industries. Due to the profound direct and indirect impacts that the built environment produces on
María José Andrade-Núñez, T. Mitchell Aide   +1 more
doaj   +1 more source

Bibliometric analysis of global research profile on ketogenic diet therapies in neurological diseases: Beneficial diet therapies deserve more attention

Frontiers in Endocrinology, 2023
BackgroundThe protective effects of Ketogenic Diet Therapies (KDTs) on neurological diseases have been extensively studied over the past two decades. The purpose of this study was to quantitatively and qualitatively analyze the publication of KDTs in the
Yinuo Wang, Junyao Zhang, Yingying Zhang, Junyan Yao   +3 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Global research progress of endothelial cells and ALI/ARDS: a bibliometric analysis

Frontiers in Physiology
BackgroundAcute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are severe respiratory conditions with complex pathogenesis, in which endothelial cells (ECs) play a key role.
Tong Zhou, Tong Zhou, Kunlan Long, Jun Chen, Lijia Zhi, Xiujuan Zhou, Peiyang Gao   +6 more
doaj   +1 more source

Spatial phylogenetics of the native woody plant species in Hainan, China

Ecology and Evolution, 2021
To better identify biodiversity hotspots for conservation on Hainan Island, a tropical island in southern China, we assessed spatial variation in phylogenetic diversity and species richness using 18,976 georeferenced specimen records and a newly ...
Zhi‐Xin Zhu, AJ Harris, Mir Muhammad Nizamani, Andrew H. Thornhill, Rosa A. Scherson, Hua‐Feng Wang   +5 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

RELATIONSHIP BETWEEN RAINFALL AND LAND COVER ON THE NUMBER OF HOTSPOTS IN LORE LINDU NATIONAL PARK

Biotropia: The Southeast Asian Journal of Tropical Biology
Forest and land fires in Indonesia need concern in handling it, specifically in conservation areas. Lore Lindu National Park (TNLL) is a conservation area that plays a role in preserving endemic plants and animals and their habitats.
Fadjri Maarif, Cesar Andi Mappatoba
doaj   +1 more source