Results 41 to 50 of about 117,481 (252)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Photovoltaic Panels Classification Using Isolated and Transfer Learned Deep Neural Models Using Infrared Thermographic Images

open access: yesSensors, 2021
Defective PV panels reduce the efficiency of the whole PV string, causing loss of investment by decreasing its efficiency and lifetime. In this study, firstly, an isolated convolution neural model (ICNM) was prepared from scratch to classify the infrared
Waqas Ahmed   +5 more
doaj   +1 more source

Hotspot Advance Speed - Hotspot Size/Core-Hotspot Length Relation

open access: yesInternational Letters of Chemistry, Physics and Astronomy, 2015
We examined the evolution of extragalactic radio sources using the observed core-hotspot length and hotspot size. Analysis indicates a fairly strong positive correlation in the ratio of core-hotspot length to hotspot size between that of the approaching arm and the receding arm with a correlation coefficient of r ~ 0.7.
openaire   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

The Implications of Global Priorities for Biodiversity and Ecosystem Services Associated with Protected Areas

open access: yesEcology and Society, 2007
Map-based prioritization systems have become ubiquitous tools for allocating resources for biological conservation. Although the scientific basis for these systems continues to be debated, they have become a significant factor in international ...
Christopher R. Pyke
doaj   +1 more source

Wildfires Risk Assessment Using Hotspot Analysis and Results Application to Wildfires Strategic Response in the Region of Tangier-Tetouan-Al Hoceima, Morocco

open access: yesFire, 2023
In recent years, changes in climate, land cover, and sociodemographic dynamics have created new challenges in wildfire management. As a result, advanced and integrated approaches in wildfire science have emerged.
Hamid Boubekraoui   +4 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Prokaryotes in subsoil – evidence for spatial separation of oligotrophs and copiotrophs by co-occurrence networks

open access: yesFrontiers in Microbiology, 2015
Soil microbial communities provide a wide range of soil functions including nutrient cycling, soil formation, and plant growth promotion. On the small scale, nutrient rich soil hotspots developed from soil animal or plant activity are important drivers ...
Michael eSchloter
doaj   +1 more source

Social Heterogeneity Drives Complex Patterns of the COVID-19 Pandemic: Insights From a Novel Stochastic Heterogeneous Epidemic Model (SHEM)

open access: yesFrontiers in Physics, 2021
In addition to vaccine and impactful treatments, mitigation strategies represent an effective way to combat the COVID-19 virus and an invaluable resource in this task is numerical modeling that can reveal key factors in COVID-19 pandemic development.
Alexander V. Maltsev, Michael D. Stern
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

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