Results 51 to 60 of about 193,140 (286)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Global research and emerging trends in depression in lung cancer: a bibliometric and visualized study from 2014 to 2024

Frontiers in Oncology
BackgroundThe impact of depression on the physical and psychological well-being of lung cancer patients has raised significant concerns. This study explored lung cancer-related depression research from a bibliometric perspective.MethodsArticles and ...
Weilan Lin, Weilan Lin, Weilan Lin, Shun Chen, Shun Chen, Shun Chen, Jiawei Chen, Jiawei Chen, Chune Wang, Chune Wang, Feng Lu, Feng Lu   +11 more
doaj   +1 more source

Photovoltaic Panels Classification Using Isolated and Transfer Learned Deep Neural Models Using Infrared Thermographic Images

Sensors, 2021
Defective PV panels reduce the efficiency of the whole PV string, causing loss of investment by decreasing its efficiency and lifetime. In this study, firstly, an isolated convolution neural model (ICNM) was prepared from scratch to classify the infrared
Waqas Ahmed, Aamir Hanif, Karam Dad Kallu, Abbas Z. Kouzani, Muhammad Umair Ali, Amad Zafar   +5 more
doaj   +1 more source

bienflorencia/Multiple-forms-of-hotspots-of-tetrapod-biodiversity

, 2020
Scripts and working examples included in the manuscript "Multiple forms of hotspots of tetrapod biodiversity and the challenges of open-access data scarcity" published in Scientific ...
Florencia Grattarola
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

The Implications of Global Priorities for Biodiversity and Ecosystem Services Associated with Protected Areas

Ecology and Society, 2007
Map-based prioritization systems have become ubiquitous tools for allocating resources for biological conservation. Although the scientific basis for these systems continues to be debated, they have become a significant factor in international ...
Christopher R. Pyke
doaj   +1 more source

Wildfires Risk Assessment Using Hotspot Analysis and Results Application to Wildfires Strategic Response in the Region of Tangier-Tetouan-Al Hoceima, Morocco

Fire, 2023
In recent years, changes in climate, land cover, and sociodemographic dynamics have created new challenges in wildfire management. As a result, advanced and integrated approaches in wildfire science have emerged.
Hamid Boubekraoui, Yazid Maouni, Abdelilah Ghallab, Mohamed Draoui, Abdelfettah Maouni   +4 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Prokaryotes in subsoil – evidence for spatial separation of oligotrophs and copiotrophs by co-occurrence networks

Frontiers in Microbiology, 2015
Soil microbial communities provide a wide range of soil functions including nutrient cycling, soil formation, and plant growth promotion. On the small scale, nutrient rich soil hotspots developed from soil animal or plant activity are important drivers ...
Michael eSchloter
doaj   +1 more source

Social Heterogeneity Drives Complex Patterns of the COVID-19 Pandemic: Insights From a Novel Stochastic Heterogeneous Epidemic Model (SHEM)

Frontiers in Physics, 2021
In addition to vaccine and impactful treatments, mitigation strategies represent an effective way to combat the COVID-19 virus and an invaluable resource in this task is numerical modeling that can reveal key factors in COVID-19 pandemic development.
Alexander V. Maltsev, Michael D. Stern
doaj   +1 more source