Results 61 to 70 of about 193,140 (286)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

The status and hotspot analysis of research on extracellular vesicles and osteoarthritis: a bibliometric analysis

open access: yesFrontiers in Pharmacology
BackgroundDegenerative joint disease, known as osteoarthritis (OA), is characterized by pain, swelling, and decreased mobility. The illness has a major negative influence on patients’ quality of life and is common around the world, especially among older
Wen Hao Zhang   +12 more
doaj   +1 more source

Responding to the Challenge

open access: yesDiaconia, 2016
We should say that in Italy the sea brings those in search of “hope.” Looking from this perspective, ”hope” for these people in Europe means starting from the concept of dignity, of having rights. It also means that you will meet people who accompany you
Davide Rosso
doaj   +1 more source

Global Research Status and Trends of Femoral Neck Fracture Over the Past 27 Years: A Historical Review and Bibliometric Analysis

open access: yesFrontiers in Surgery, 2022
BackgroundFemoral neck fracture (FNF) is a commonly encountered injury in orthopedic practice, and many studies have been conducted in this field. However, no bibliometric studies regarding the global research trend concerning FNF have been performed ...
Peng Peng   +19 more
doaj   +1 more source

Hotspots: Modelling capacity for vector-borne disease risk analysis in New Zealand: A case study of Ochlerotatus camptorhynchus incursions in New Zealand [PDF]

open access: yes, 2005
This Hotspots case study of Oc. camptorhynchus in New Zealand forms part of the wider aims and objectives of the Hotspots project. The overall aims of the case study were: 1. To evaluate the performance of the Hotspots model as a risk analysis tool for
de Wet, Neil   +4 more
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Schizophrenia and Inflammation Research: A Bibliometric Analysis

open access: yesFrontiers in Immunology, 2022
BackgroundSchizophrenia (SCZ) is a severe psychiatric disorder that involves inflammatory processes. The aim of this study was to explore the field of inflammation-related research in SCZ from a bibliometric perspective.MethodsRegular and review articles
He-Li Sun   +15 more
doaj   +1 more source

Hotspot advance speed - hotspot size/core-hotspot distance relation

open access: yesRwanda Journal, 2016
We examined the evolution of extragalactic radio sources using the observed corehotspot distance and hotspot size. Analysis indicates a fairly strong positive correlation in the ratio of core-hotspot distance to hotspot size between that of the approaching arm and the receding arm with a correlation coefficient of r ~ 0.7.
openaire   +3 more sources

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

Global trends of acupuncture clinical research on analgesia from 2010 to 2023: a bibliometric and visualization analysis

open access: yesFrontiers in Neurology
ObjectiveAcupuncture, acknowledged as a potent non-pharmacological therapy, is frequently employed to alleviate pain. Despite its widespread use, there has been a lack of overarching bibliometric analysis of clinical research on acupuncture analgesia. We
Zhi-Qiang Li   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy