Results 51 to 60 of about 80,667 (289)

Uso de medicamentos potencialmente inadecuados en pacientes mayores con necesidades de atención paliativa en atención domiciliaria. Estudio transversal

open access: yesMedUNAB
RESUMEN Introducción. El envejecimiento poblacional ha incrementado la prevalencia de enfermedades crónicas como el trastorno neurocognoscitivo mayor, la multimorbilidad, la polifarmacia y con esto la probabilidad de prescripciones potencialmente ...
Ana Carolina Gama-González   +3 more
doaj   +1 more source

A Model for Out-of-Hospital Multispecialty Emergency Medicine: Accomplishments and Challenges

open access: yesHealth Services Insights, 2018
Home care has been traditionally considered as an important type of medical service. “SOS Doctors” is a Greek organization providing out-of-hospital multispecialty emergency medicine services the past 25 years. Its services mainly meet the demands of the
George Theocharis   +6 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

A Posthospitalization Home Visit Curriculum for Pediatric Patients

open access: yesMedEdPORTAL, 2020
Introduction Home visits allow physicians to develop a deeper understanding of patients' homes and community, enhance physician-patient connectedness, and improve physician treatment plans for patients.
Eric Balighian   +6 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

POGOe: Healthy Ager Life History Project

open access: yesMedEdPORTAL, 2007
This resource trains students how to gather a life history from a “healthy ager,” someone who is defined as being over the age of 60. Students are trained in class and then meet with an assigned older adult to conduct the life history.
Lynn Bickley
doaj   +1 more source

Befriending the Darkness: L.M. Montgomery's Lived Theodicy in Anne's House of Dreams

open access: yesJournal of L.M. Montgomery Studies, 2021
In Anne's House of Dreams, which Elizabeth Epperly calls Montgomery's most philosophical novel, Montgomery delves into painful topics of loss, suicide, bad marriages, ill-timed love, poverty, and the beautiful-terrible consequences of duty. The result is
Brenton D.G. Dickieson
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Acceptability and feasibility of a comprehensive fall prevention model for independent older adults: A qualitative evaluation

open access: yesInternational Journal of Nursing Studies Advances
Background: Falls amongst the elderly represent a global public health challenge because of their potential to cause illness, death, and reduce the autonomy of this group.
Francisca Marquez-Doren   +4 more
doaj   +1 more source

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