Results 141 to 150 of about 21,981 (273)

Structural Basis for Trivalent Cross‐Linking of a Patient‐Derived IgE Antibody by the Major Peanut Allergen Ara h 2.0201

Allergy, Volume 81, Issue 6, Page 2036-2046, June 2026.
Graphical The crystal structure of a major peanut allergen Ara h 2.0201 in a complex with a human‐derived IgE Fab fragment has been determined. The immunocomplex shows the trivalent binding of Fabs, creating a cross‐linked structure effective in the formation of large complexes on the surface of effector cells. Hydroxylation of proline has implications
Tarja Parkkinen, Heidi Heiniluoto, Janne Jänis, Kristiina Takkinen, Juha Rouvinen   +4 more
wiley   +1 more source

Combined Exposure to Ragweed and House Dust Mite Exacerbates Airway Epithelial Barrier Dysfunction: A Multimodal Approach. [PDF]

Medicina (Kaunas)
Zimbru EL, Zimbru RI, Grijincu M, Bojin FM, Buzan MR, Chiriac SD, Tănasie G, Haidar L, Calma CL, Panaitescu C.   +9 more
europepmc   +1 more source

A One‐Strength Dose Escalation Regimen for Birch Pollen Subcutaneous Immunotherapy Is Safe and Tolerable in Children, Adolescents, and Adults

Allergy, Volume 81, Issue 6, Page 2079-2088, June 2026.
This study evaluated safety and tolerability of birch pollen SCIT during dose escalation with a new One‐Strength regimen (3 injections, Strength B) compared to the Standard regimen (7 injections, Strengths A and B) in patients aged 5–65 years. Safety and tolerability were comparable between the two regimens in adults, adolescents, and adolescents, as ...
Marek Jutel, Ludger Klimek, Michael Gerstlauer, Dana Troyke, Kristina Duwensee, Christian Vogelberg   +5 more
wiley   +1 more source

Immunological effects of subcutaneous and sublingual immunotherapy in house dust mite-allergic adults: a nine-month prospective pilot study. [PDF]

Sci Rep
Taha SI, Shaban AT, Mostafa AA, Ghonaim SS, Salem L.   +4 more
europepmc   +1 more source

Patient‐Perceived Benefits of Named‐Patient Product Sublingual Immunotherapy in Allergic Rhinitis and Asthma: Primary Results From the ERAPP Real‐World Cohort Study

Allergy, Volume 81, Issue 6, Page 2145-2155, June 2026.
Evaluation en vie Réelle de l'Allergo‐Prescription en Pratique (ERAPP) is a large, prospective, real‐world cohort of children and adults initiating named‐patient product sublingual immunotherapy (NPP‐SLIT) in France. More than 80% of patients reported a clinically meaningful, expectation‐anchored benefit (Patient Benefit Index ≥ 1) at 12–15 months. The
Davide Caimmi, Abdelilah Abouelfath, Régis Lassalle, Séverine Lignot‐Maleyran, Emmanuelle Bignon, Patrick Blin, Evangéline Clark, Julien Cottet, Laure Carcaillon‐Bentata, Pascal Demoly   +9 more
wiley   +1 more source

Comorbidity of Allergic Asthma and Rhinitis and High Allergen-Specific IgE are Risk Factors for Systemic Reactions to House Dust Mite Immunotherapy in Children. [PDF]

J Asthma Allergy
Wang Q, Dong X, Zhu S, Yuan L, Wang H, Zhao R, Dong N.   +6 more
europepmc   +1 more source

Allergic rhinitis activity and efficacy of 300 IR house dust mite sublingual immunotherapy tablet in pediatrics. [PDF]

Pediatr Allergy Immunol
Devillier P, Okano M, Canonica GW, Scurati S, Cognet-Sicé J, Gentil C, Yan K, Cottet J, Fromentin E, Demoly P, Pfaar O, Okamoto Y.   +11 more
europepmc   +1 more source

Medicine for the Material World

Archaeometry, Volume 68, Issue 3, Page 434-439, June 2026.
ABSTRACT It is clear that many of the inorganic materials of antiquity have been used both as medicines for human ills and also as agents in technological processes. This paper speculates that there might have been a stronger link between these two functions in the past, based on the concept of “active agents”—materials that are efficacious at curing ...
A. M. Pollard
wiley   +1 more source

Two combinations of house dust mite allergens show similar performance than extracts for asthma diagnosis. [PDF]

Front Allergy
Marrugo V, Zakzuk J, Reina R, Donado K, Regino R, Gil I, Meza C, Mercado D, Fernández-Caldas E, Puerta L, Acevedo N, Caraballo L.   +11 more
europepmc   +1 more source

A Walk in the Park: Influence of Natural Co‐Exposure to Grass Pollen and Fungal Spores on Nasal Mycobiome and Cytokine Responses

Clinical &Experimental Allergy, Volume 56, Issue 6, Page 617-628, June 2026.
Volunteers stayed 3 h indoors and followed 1 h outdoors in a flowering meadow. Nasal mycobiome was analysed and aeroallergen content measured in nasal filters. Airborne fungal spores were quantified and fungal isolates were sequenced. Isolated fungal spores were used for stimulation of nasal epithelial cells.
Annika Eggestein, Denise Rauer, Selina M. Herrmann, Franziska Kolek, Vivien Leier‐Wirtz, Swetlana Urban, Bärbel Foesel, Michael Schloter, Madhumita Bhattacharyya, Ioana Pyrri, Matthias Reiger, Vera Schwierzeck, Claudia Hülpüsch, Claudia Traidl‐Hoffmann, Athanasios Damialis, Stefanie Gilles   +15 more
wiley   +1 more source