Results 61 to 70 of about 17,263 (216)

House dust mite allergy – Management

open access: yesIndian Journal of Allergy Asthma and Immunology
Allergen vulnerability is highly individual specific. House dust mites (HDMs) are major sources of airborne allergens, found not only in houses but also detected in workplaces and most schools.
P. C. Kathuria, Manisha Rai
doaj   +1 more source

Proteome and allergenome of the European house dust mite Dermatophagoides pteronyssinus.

open access: yesPLoS ONE, 2019
The European house dust mite Dermatophagoides pteronyssinus is of significant medical importance as it is a major elicitor of allergic illnesses.
Rose Waldron   +5 more
doaj   +1 more source

House dust mite sensitisation and association with atopic dermatitis in Brunei

open access: yesClinical and Translational Allergy, 2019
IgE sensitisation in tropical areas is under-reported. A 2 year retrospective cohort study of allergy data specific to aero and food allergens in Brunei demonstrated that specific IgE levels to house dust mite (Dermatophagoides pteronyssinus, D.farinae ...
Haziq Emran   +3 more
doaj   +1 more source

Mapping Allergen B‐ and T‐Cell Epitopes: Technological Advances and Their Role in Precision Allergy Therapy

open access: yesAllergy, EarlyView.
ABSTRACT Allergic diseases arise from aberrant immune recognition of otherwise harmless environmental proteins and are driven by epitope‐specific interactions between allergens and the adaptive immune system. Although component‐resolved diagnostics have improved molecular characterisation of sensitization, they remain limited to whole‐allergen ...
Mark Møiniche   +11 more
wiley   +1 more source

Dendritic Cell α‐Ketoglutarate Regulates Tfh Polarization in Allergy

open access: yesAllergy, EarlyView.
Allergen induces a dendritic cell metabolism shift toward glutaminolysis with α‐ketoglutarate as a regulator of Tfh subset polarization. Glutaminolysis is required for DC allergen uptake, co‐stimulatory molecule expression, and CLR expression. Modulation of glutaminolysis, JmjD3 histone demethylation, or HIF‐1α degradation alters Tfh polarization and ...
Anuj Tharakan   +16 more
wiley   +1 more source

lncRNA profiling in NCI-H292 cells after stimulation with Dermatophagoides farinae extracts

open access: yesInternational Journal of Immunopathology and Pharmacology, 2018
Airway epithelium cells are the first line of defense against airborne allergens. When cultured, epithelial cells can be exposed to various allergens, providing an ideal model to investigate allergic disorders.
Lilei Wang, Ying Zhou, Yubao Cui
doaj   +1 more source

Deficiency of Mitochondrial Fatty Acid Enzyme, CPT1A, Underlies Airway Epithelial Barrier Dysfunction in Severe Asthma

open access: yesAllergy, EarlyView.
Mitochondrial fatty acid enzyme, CPT1A, is deficient in the airway epithelium of severe asthma patients. Restoration of CPT1A expression improved epithelial barrier integrity via increasing mitochondrial respiration and ATP production in airway epithelial cells. Restoration of deficient epithelial CPT1A may represent a new treatment approach for severe
Muyun Wang   +12 more
wiley   +1 more source

Route of Allergen Immunotherapy: A Global Look Into Physicians' Motivations

open access: yesAllergy, EarlyView.
Little is known about the factors driving AIT prescription in clinical practice, including the level of personalization from patient to patient. Patient‐centred factors theoretically would favour SLIT prescription. Doctors’ knowledge, training, and country influence the final decision on the route.
Carmen Vidal   +42 more
wiley   +1 more source

Efficacy and safety of house dust mite cluster immunotherapy in the treatment of allergic rhinitis and asthma: a multicenter prospective single-arm interventional study [PDF]

open access: yesXin yixue
Objective To investigate the efficacy and safety of 4-week cluster immunotherapy with house dust mite extracts in patients allergic to house dust mites.
SHANG Tengze, LI Lisha, WANG Qing, DENG Baiyu, ZHANG Xiaoli, HUANG Yan, JIN Xiuhong, MENG Wenxia, YAO Hui, GUAN Kai
doaj   +1 more source

Classification of Seasonal Allergic Rhinitis Patients by Prospective Patient‐Recorded Symptoms: The @IT.2020 Project

open access: yesAllergy, EarlyView.
Daily prospective symptom reports from participants in this multicentre observational study were compared to retrospective (last 12 months) reports based on ARIA clinical questionnaire. Retrospective reports substantially underestimated, and to a lesser extent overestimated, symptom frequency compared to e‐Diary prospective reports. Since retrospective
Stephanie Dramburg   +56 more
wiley   +1 more source

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