Results 31 to 40 of about 17,040 (303)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Reform of the House of Lords in British politics 1970-1992. [PDF]

open access: yes, 2005
PhDPerceived obstruction of the Labour government's legislative programme in the mid-1970s sparked renewed interest in tackling the House of Lords.
Lamport, Timothy Ennis
core  

Attempts to change the British House of Lords into a second chamber of the nations and regions: explaining a history af failed reforms

open access: yesPerspectives on Federalism, 2018
The House of Lords is the world’s longest-established and probably best-known second chamber. Wholly unelected, with most members appointed for life, it appears a vestige of the ‘elite’ form of bicameralism once common throughout Europe.
Russell Meg
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Written evidence, Dr Caroline Moraes, Birmingham Business School, University of Birmingham, UK (CCE0019) [PDF]

open access: yes, 2022
Written Evidence submitted to the UK Parliament, House of Lords Environment and Climate Change Committee (submission reference number IXD889257, call available at https://committees.parliament.uk/call-for-evidence/628/).
Moraes, Caroline; id_orcid
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Reform of the House of Lords [PDF]

open access: yes, 2008
Hope of Craighead David. The Reform of the House of Lords. In: Revue internationale de droit comparé. Vol. 60 N°2,2008. pp.
Hope of Craighead, David
core   +1 more source

The Right Way Through the Region of Sin: Islam, Bioethics and New Reproductive Technologies

open access: yesEtnoantropološki Problemi, 2010
In the 1980s numerous debates were held in the House of Lords on the scientific research of embryos, with certain participants attempting to point out the difference between two styles of thought, namely, religious and scientific thought.
Marko Pišev
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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